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Richard R Sprenger

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Articles 37
Citations 766
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Recent Articles
1.
Sprenger R, Bilgin M, Ostenfeld M, Bjornshave A, Rasmussen J, Ejsing C
Food Res Int . 2024 Jun; 190:114601. PMID: 38945615
Lipids from cow milk fat globule membranes (MFGMs) and extracellular vesicles (EVs) are considered beneficial for neurodevelopment, cognitive maintenance and human health in general. Nevertheless, it is largely unknown whether...
2.
Gopalan A, van Uden L, Sprenger R, Fernandez-Novel Marx N, Bogetofte H, Neveu P, et al.
Life Sci Alliance . 2024 Feb; 7(5). PMID: 38418090
During development, different tissues acquire distinct lipotypes that are coupled to tissue function and homeostasis. In the brain, where complex membrane trafficking systems are required for neural function, specific glycerophospholipids,...
3.
Sprenger R, Ostenfeld M, Bjornshave A, Rasmussen J, Ejsing C
Biomolecules . 2024 Jan; 14(1). PMID: 38254655
Lipids from milk fat globule membranes (MFGMs) and extracellular vesicles (EVs) are considered beneficial for cognitive development and human health. Milk-derived whey concentrates rich in these lipids are therefore used...
4.
Khalil S, Sprenger R, Hermansson M, Ejsing C
J Mass Spectrom . 2022 Sep; 57(9):e4882. PMID: 36055222
Matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) is a useful technique for visualizing the spatial distribution of lipid molecules in tissues. Nevertheless, the use of MSI to investigate local lipid metabolic...
5.
Henriksen N, Hansen S, Lycas M, Pan X, Eriksen T, Johansen L, et al.
Physiol Rep . 2022 Jul; 10(13):e15368. PMID: 35822260
Infants with neonatal cholestasis are prone to neurodevelopmental deficits, however, the underlying pathogenesis is unclear. Lipid malabsorption and accumulation of potentially neurotoxic molecules in the blood such as bile acids...
6.
Henriksen N, Asmussen K, Pan X, Jiang P, Mori Y, Christiansen L, et al.
Sci Rep . 2022 Mar; 12(1):3303. PMID: 35228576
Breast milk has neurodevelopmental advantages compared to infant formula, especially in low-birth-weight infants, which may in part relate to the fat source. This study compared neurodevelopmental outcomes in three-day-old normal...
7.
Renne M, Bao X, Hokken M, Bierhuizen A, Hermansson M, Sprenger R, et al.
EMBO J . 2021 Dec; 41(2):e106837. PMID: 34873731
Mitochondria depend on the import of phospholipid precursors for the biosynthesis of phosphatidylethanolamine (PE) and cardiolipin, yet the mechanism of their transport remains elusive. A dynamic lipidomics approach revealed that...
8.
Schmidt S, Gallego S, Zelnik I, Kovalchuk S, Albaek N, Sprenger R, et al.
Mol Ther . 2021 Aug; 30(4):1661-1674. PMID: 34400330
Emerging clinical data show that three ceramide molecules, Cer d18:1/16:0, Cer d18:1/24:1, and Cer d18:1/24:0, are biomarkers of a fatal outcome in patients with cardiovascular disease. This finding raises basic...
9.
Henriksen N, Aasmul-Olsen K, Venkatasubramanian R, Nygaard M, Sprenger R, Heckmann A, et al.
Nutrients . 2021 Mar; 13(3). PMID: 33668360
Breastfed infants have higher intestinal lipid absorption and neurodevelopmental outcomes compared to formula-fed infants, which may relate to a different surface layer structure of fat globules in infant formula. This...
10.
Sprenger R, Hermansson M, Neess D, Becciolini L, Sorensen S, Fagerberg R, et al.
Cell Rep . 2021 Feb; 34(5):108710. PMID: 33535053
Diurnal regulation of whole-body lipid metabolism plays a vital role in metabolic health. Although changes in lipid levels across the diurnal cycle have been investigated, the system-wide molecular responses to...