Richard P Novick
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Explore the profile of Richard P Novick including associated specialties, affiliations and a list of published articles.
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91
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6189
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Recent Articles
1.
Ram G, Chiu L, Dey S, Ross H, Cammer M, Novick R
Antimicrob Agents Chemother
. 2024 Jul;
68(9):e0023524.
PMID: 39072634
In response to the antimicrobial resistance crisis, we have developed a powerful and versatile therapeutic platform, the Antibacterial Drone (ABD) system. The ABD consists of a highly mobile staphylococcal pathogenicity...
2.
3.
Zhao A, Bodine S, Xie Q, Wang B, Ram G, Novick R, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(33):e2202661119.
PMID: 35939668
In virulence is under the control of a quorum sensing (QS) circuit encoded in the accessory gene regulator () genomic locus. Key to this pathogenic behavior is the production and...
4.
Dhasmana N, Ram G, McAllister K, Chupalova Y, Lopez P, Ross H, et al.
mBio
. 2021 Nov;
12(6):e0208321.
PMID: 34781740
The antibacterial drone (ABD) system is based on repurposing the phage-inducible staphylococcal pathogenicity islands (SaPIs) for use as antibacterial agents that are indifferent to antibiotic resistance. The ABDs were constructed...
5.
Novick R
Curr Opin Microbiol
. 2021 Oct;
64:109-116.
PMID: 34688038
This review is focused on the subset of antibacterial agents whose action involves one-on-one targeting of infecting bacteria. These agents target individual bacteria and their efficacy is based on particle...
6.
Haag A, Podkowik M, Ibarra-Chavez R, Gallego Del Sol F, Ram G, Chen J, et al.
Nat Microbiol
. 2021 Sep;
6(10):1300-1308.
PMID: 34518655
Staphylococcal pathogenicity islands (SaPIs) are a family of closely related mobile chromosomal islands that encode and disseminate the superantigen toxins, toxic shock syndrome toxin 1 and superantigen enterotoxin B (SEB)....
7.
Xie Q, Wiedmann M, Zhao A, Pagan I, Novick R, Suga H, et al.
Chem Commun (Camb)
. 2020 Aug;
56(76):11223-11226.
PMID: 32820778
We combined mRNA display technology with lipid-nanodisc based selections and identified high-affinity ligands targeting the integral membrane sensor domain of the histidine kinase AgrC as potent inhibitors of Staphylococcus aureus...
8.
Novick R
Microbiol Spectr
. 2019 Jun;
7(3).
PMID: 31172913
Pathogenicity islands are members of a vast collection of genomic islands that encode important virulence, antibiotic resistance and other accessory functions and have a critical role in bacterial gene transfer....
9.
Xie Q, Zhao A, Jeffrey P, Kim M, Bassler B, Stone H, et al.
Cell Chem Biol
. 2019 Feb;
26(4):548-558.e4.
PMID: 30773482
Virulence induction in the Staphylococcus aureus is under the control of a quorum sensing (QS) circuit encoded by the accessory gene regulator (agr) locus. Allelic variation within agr produces four...
10.
Ram G, Ross H, Novick R, Rodriguez-Pagan I, Jiang D
Nat Biotechnol
. 2018 Sep;
36(10):971-976.
PMID: 30247487
Staphylococcus aureus and other staphylococci continue to cause life-threatening infections in both hospital and community settings. They have become increasingly resistant to antibiotics, especially β-lactams and aminoglycosides, and their infections...