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Richard N Kitsis

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Articles 111
Citations 9320
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Recent Articles
1.
Qin D, Modanwal R, Kitsis R
Circulation . 2024 Nov; 150(22):1812-1814. PMID: 39585932
No abstract available.
2.
Liang F, Zandkarimi F, Lee J, Axelrod J, Pekson R, Yoon Y, et al.
Mol Cell . 2024 Aug; 84(16):3098-3114.e6. PMID: 39142278
Ferroptosis, an iron-dependent form of nonapoptotic cell death mediated by lipid peroxidation, has been implicated in the pathogenesis of multiple diseases. Subcellular organelles play pivotal roles in the regulation of...
3.
Liang F, Moslehi J, Kitsis R
Circ Res . 2024 Feb; 134(5):502-504. PMID: 38422183
No abstract available.
4.
Salloum F, Tocchetti C, Ameri P, Ardehali H, Asnani A, de Boer R, et al.
JACC CardioOncol . 2024 Jan; 5(6):715-731. PMID: 38205010
Despite improvements in cancer survival, cancer therapy-related cardiovascular toxicity has risen to become a prominent clinical challenge. This has led to the growth of the burgeoning field of cardio-oncology, which...
5.
Pekson R, Liang F, Axelrod J, Lee J, Qin D, Wittig A, et al.
Proc Natl Acad Sci U S A . 2023 Dec; 120(51):e2303713120. PMID: 38091291
The mitochondrial permeability transition pore (mPTP) is a channel in the inner mitochondrial membrane whose sustained opening in response to elevated mitochondrial matrix Ca concentrations triggers necrotic cell death. The...
6.
Miao R, Jiang C, Chang W, Zhang H, An J, Ho F, et al.
Immunity . 2023 Nov; 56(11):2523-2541.e8. PMID: 37924812
Gasdermin D (GSDMD)-activated inflammatory cell death (pyroptosis) causes mitochondrial damage, but its underlying mechanism and functional consequences are largely unknown. Here, we show that the N-terminal pore-forming GSDMD fragment (GSDMD-NT)...
7.
Qin D, Jia X, Hanna A, Lee J, Pekson R, Elrod J, et al.
J Mol Cell Cardiol . 2023 Sep; 184:1-12. PMID: 37709008
At least seven cell death programs are activated during myocardial infarction (MI), but which are most important in causing heart damage is not understood. Two of these programs are mitochondrial-dependent...
8.
9.
Axelrod J, Pekson R, Kitsis R
J Mol Cell Cardiol . 2023 Jul; 182:73-74. PMID: 37453667
No abstract available.
10.
Vitale I, Pietrocola F, Guilbaud E, Aaronson S, Abrams J, Adam D, et al.
Cell Death Differ . 2023 Apr; 30(5):1097-1154. PMID: 37100955
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have...