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Richard M Watson

Explore the profile of Richard M Watson including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 584
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Recent Articles
1.
Kierzek E, Zhang X, Watson R, Kennedy S, Szabat M, Kierzek R, et al.
Nat Commun . 2022 Mar; 13(1):1271. PMID: 35277476
There is increasing interest in the roles of covalently modified nucleotides in RNA. There has been, however, an inability to account for modifications in secondary structure prediction because of a...
2.
Al-Sajee D, Sehmi R, Hawke T, El-Gammal A, Howie K, Watson R, et al.
Am J Respir Crit Care Med . 2018 May; 198(6):805-807. PMID: 29733677
No abstract available.
3.
Oliveria J, El-Gammal A, Yee M, Obminski C, Scime T, Watson R, et al.
J Allergy Clin Immunol . 2017 Dec; 141(4):1495-1498.e9. PMID: 29221714
No abstract available.
4.
Blais C, Cockcroft D, Veilleux J, Boulay M, Boulet L, Gauvreau G, et al.
J Aerosol Med Pulm Drug Deliv . 2017 Aug; 31(2):88-93. PMID: 28813613
Background: The latest methacholine challenge testing (MCT) guidelines published by the European Respiratory Society recommend the characterization of nebulizers before their use in clinics and research. Such investigations are necessary...
5.
Mathews D, Turner D, Watson R
Curr Protoc Nucleic Acid Chem . 2016 Dec; 67:11.2.1-11.2.19. PMID: 27911493
In this unit, protocols are provided for predicting RNA secondary structure with the user-friendly RNAstructure desktop computer program and the RNAstructure Web server. The minimum free energy structure and a...
6.
Todd C, Salter B, Murphy D, Watson R, Howie K, Milot J, et al.
Pulm Pharmacol Ther . 2016 Sep; 41:34-39. PMID: 27640067
Background: Neutrophils are effector cells recruited to airways in patients with asthma. Migration of neutrophils occurs predominantly through activation of the CXCR1 and CXCR2 receptors by CXC chemokines, including IL-8...
7.
Gauvreau G, Arm J, Boulet L, Leigh R, Cockcroft D, Davis B, et al.
J Allergy Clin Immunol . 2016 May; 138(4):1051-1059. PMID: 27185571
Background: Omalizumab is an established anti-IgE therapy for the treatment of allergic diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE antibody that binds IgE...
8.
Lerner C, Sundar I, Watson R, Elder A, Jones R, Done D, et al.
Environ Pollut . 2015 Jan; 198:100-7. PMID: 25577651
To narrow the gap in our understanding of potential oxidative properties associated with Electronic Nicotine Delivery Systems (ENDS) i.e. e-cigarettes, we employed semi-quantitative methods to detect oxidant reactivity in disposable...
9.
Gauvreau G, Boulet L, Leigh R, Cockcroft D, Killian K, Davis B, et al.
Am J Respir Crit Care Med . 2014 Dec; 191(2):161-7. PMID: 25473939
Rationale: Effective antiinflammatory therapies are needed for the treatment of asthma, but preferably without the systemic adverse effects of glucocorticosteroids. Objectives: We evaluated the effect of an inhaled nonsteroidal glucocorticoid...
10.
Gauvreau G, Boulet L, Schmid-Wirlitsch C, Cote J, Duong M, Killian K, et al.
Respir Res . 2011 Oct; 12:140. PMID: 22029856
Background: Phosphodiesterase 4 (PDE4) inhibitors increase intracellular cyclic adenosine monophosphate (cAMP), leading to regulation of inflammatory cell functions. Roflumilast is a potent and targeted PDE4 inhibitor. The objective of this...