Karen J Howie
Overview
Explore the profile of Karen J Howie including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
299
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0
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Recent Articles
1.
Jeyanathan M, Fritz D, Afkhami S, Aguirre E, Howie K, Zganiacz A, et al.
JCI Insight
. 2022 Jan;
7(3).
PMID: 34990408
BackgroundAdenovirus-vectored (Ad-vectored) vaccines are typically administered via i.m. injection to humans and are incapable of inducing respiratory mucosal immunity. However, aerosol delivery of Ad-vectored vaccines remains poorly characterized, and its...
2.
Cockcroft D, Davis B, Blais C, Boulet L, Boulay M, Villeneuve H, et al.
Allergy Asthma Clin Immunol
. 2019 Dec;
15:73.
PMID: 31788006
Background: Allergen inhalation tests are a valuable research tool. The allergen dose producing an early asthmatic response (EAR) can be predicted from methacholine responsiveness and allergen skin test endpoint (STE)....
3.
Al-Sajee D, Sehmi R, Hawke T, El-Gammal A, Howie K, Watson R, et al.
Am J Respir Crit Care Med
. 2018 May;
198(6):805-807.
PMID: 29733677
No abstract available.
4.
Todd C, Salter B, Murphy D, Watson R, Howie K, Milot J, et al.
Pulm Pharmacol Ther
. 2016 Sep;
41:34-39.
PMID: 27640067
Background: Neutrophils are effector cells recruited to airways in patients with asthma. Migration of neutrophils occurs predominantly through activation of the CXCR1 and CXCR2 receptors by CXC chemokines, including IL-8...
5.
Allakhverdi Z, Comeau M, Armant M, Agrawal R, Woodfolk J, Sehmi R, et al.
Front Immunol
. 2014 Jan;
4:461.
PMID: 24381572
Background: Shortly after allergen exposure, the number of bone marrow (BM) and circulating CD34(+) progenitors increases. We aim to analyze the possible mechanism whereby the allergic reaction stimulates BM to...
6.
Sohani Z, Strinich T, Watson B, Smith S, Torek A, Howie K, et al.
J Asthma
. 2011 Oct;
48(9):952-6.
PMID: 22014007
Objective: Induced sputum is used to assess markers of inflammation in asthmatic individuals, and sputum cell differential counts provide an outcome to evaluate the presence, type, and degree of inflammation...
7.
Gauvreau G, Boulet L, Cockcroft D, FitzGerald J, Carlsten C, Davis B, et al.
Am J Respir Crit Care Med
. 2010 Nov;
183(8):1007-14.
PMID: 21057005
Rationale: Extensive evidence in animal models supports a role for IL-13 in the pathobiology of asthma. IMA-638 and IMA-026 are fully humanized IgG(1) antibodies that bind to different epitopes and...
8.
Allakhverdi Z, Comeau M, Smith D, Toy D, Endam L, Desrosiers M, et al.
J Allergy Clin Immunol
. 2008 Dec;
123(2):472-8.
PMID: 19064280
Background: In steady state, hemopoietic progenitors constantly egress from the bone marrow (BM) into the blood and circulate through the peripheral tissues. In allergic diseases, the BM releases increased numbers...
9.
Catalli A, Thomson J, Babirad I, Duong M, Doyle T, Howie K, et al.
J Allergy Clin Immunol
. 2008 Sep;
122(4):803-810.
PMID: 18760454
Background: Mobilization of hemopoietic progenitor cells from the bone marrow (BM) is a feature of inflammatory asthmatic responses. Understanding the mechanisms regulating progenitor cell mobilization and trafficking to the peripheral...