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Richard M Harland

Explore the profile of Richard M Harland including associated specialties, affiliations and a list of published articles. Areas
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Articles 126
Citations 4196
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Recent Articles
1.
Gandhi S, Du E, Pangilinan E, Harland R
bioRxiv . 2024 Nov; PMID: 39574688
The Wnt1-Cre2 driver, designed to address the effect of Wnt1 overactivation in the ventral neural tube in the original Wnt1-Cre line, was recently shown to have ectopic expression in the...
2.
Kotov A, Seal S, Alkobtawi M, Kappes V, Ruiz S, Arbes H, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2311685121. PMID: 38683994
Neural crest cells exemplify cellular diversification from a multipotent progenitor population. However, the full sequence of early molecular choices orchestrating the emergence of neural crest heterogeneity from the embryonic ectoderm...
3.
Harland R, Wallingford J
Cells Dev . 2024 Mar; :203910. PMID: 38452855
One hundred years ago, Hilde Mangold and Hans Spemann published their seminal paper on what came to be known as The Organizer, but seven decades would pass before the molecular...
4.
Bredeson J, Mudd A, Medina-Ruiz S, Mitros T, Smith O, Miller K, et al.
Nat Commun . 2024 Jan; 15(1):579. PMID: 38233380
Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate cell and developmental model systems, notably the genus Xenopus. Here we report a high-quality...
5.
Sive H, Harland R
Cold Spring Harb Protoc . 2022 Oct; 2023(5):pdb.top106195. PMID: 36283836
Collecting eggs from adult and to raise healthy embryos and tadpoles is relatively simple but requires careful handling of the frog. Eggs can be fertilized through natural matings or by...
6.
Harland R, Sive H
Cold Spring Harb Protoc . 2022 Sep; 2023(1):19-21. PMID: 36167670
Adult frogs that are well-cared-for will give high-quality eggs and embryos for use in every protocol. Thoughtful frog husbandry is thus pivotal to successful research using these organisms. Protocols for...
7.
Evans B, Mudd A, Bredeson J, Furman B, Wasonga D, Lyons J, et al.
J Evol Biol . 2022 Sep; 35(12):1777-1790. PMID: 36054077
In many groups, sex chromosomes change frequently but the drivers of their rapid evolution are varied and often poorly characterized. With an aim of further understanding sex chromosome turnover, we...
8.
DeJong C, Dichmann D, Exner C, Xu Y, Harland R
Development . 2021 Aug; 148(15). PMID: 34345915
The FET family of atypical RNA-binding proteins includes Fused in sarcoma (FUS), Ewing's sarcoma (EWS) and the TATA-binding protein-associate factor 15 (TAF15). FET proteins are highly conserved, suggesting specialized requirements...
9.
Willsey H, Exner C, Xu Y, Everitt A, Sun N, Wang B, et al.
Neuron . 2021 Apr; 109(8):1409. PMID: 33887193
No abstract available.
10.
Willsey H, Exner C, Xu Y, Everitt A, Sun N, Wang B, et al.
Neuron . 2021 Jan; 109(5):788-804.e8. PMID: 33497602
Gene Ontology analyses of autism spectrum disorders (ASD) risk genes have repeatedly highlighted synaptic function and transcriptional regulation as key points of convergence. However, these analyses rely on incomplete knowledge...