Richard M Harland
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Explore the profile of Richard M Harland including associated specialties, affiliations and a list of published articles.
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126
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4196
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Recent Articles
11.
Willsey H, Xu Y, Everitt A, Dea J, Exner C, Willsey A, et al.
Development
. 2020 Dec;
147(23).
PMID: 33288503
No abstract available.
12.
Willsey H, Xu Y, Everitt A, Dea J, Exner C, Willsey A, et al.
Development
. 2020 May;
147(21).
PMID: 32467234
[dual specificity tyrosine-(Y)-phosphorylation-regulated kinase 1 A] is a high-confidence autism risk gene that encodes a conserved kinase. In addition to autism, individuals with putative loss-of-function variants in exhibit microcephaly, intellectual...
13.
Kjolby R, Truchado-Garcia M, Iruvanti S, Harland R
Development
. 2019 Jul;
146(15).
PMID: 31285353
During gastrulation, Wnt and FGF signaling pathways cooperate to induce posterior structures. Wnt target expression around the blastopore falls into two main categories: a horseshoe shape with a dorsal gap,...
14.
Mitros T, Lyons J, Session A, Jenkins J, Shu S, Kwon T, et al.
Dev Biol
. 2019 Apr;
452(1):8-20.
PMID: 30980799
The Western clawed frog Xenopus tropicalis is a diploid model system for both frog genetics and developmental biology, complementary to the paleotetraploid X. laevis. Here we report a chromosome-scale assembly...
15.
Zhou X, Zhang Y, Michal J, Qu L, Zhang S, Wildung M, et al.
Cell Mol Life Sci
. 2019 Feb;
76(11):2185-2198.
PMID: 30729254
RNA alternative polyadenylation contributes to the complexity of information transfer from genome to phenome, thus amplifying gene function. Here, we report the first X. tropicalis resource with 127,914 alternative polyadenylation...
16.
Sun D, Tasca A, Haas M, Baltazar G, Harland R, Finkbeiner W, et al.
Cells Tissues Organs
. 2018 Oct;
205(5-6):279-292.
PMID: 30300884
Na+/H+ exchangers (NHEs) represent a highly conserved family of ion transporters that regulate pH homeostasis. NHEs as well as other proton transporters were previously linked to the regulation of the...
17.
Willsey H, Walentek P, Exner C, Xu Y, Lane A, Harland R, et al.
Dev Biol
. 2018 Aug;
442(2):276-287.
PMID: 30096282
Microtubule remodeling is critical for cellular and developmental processes underlying morphogenetic changes and for the formation of many subcellular structures. Katanins are conserved microtubule severing enzymes that are essential for...
18.
19.
Plouhinec J, Medina-Ruiz S, Borday C, Bernard E, Vert J, Eisen M, et al.
PLoS Biol
. 2017 Oct;
15(10):e2004045.
PMID: 29049289
During vertebrate neurulation, the embryonic ectoderm is patterned into lineage progenitors for neural plate, neural crest, placodes and epidermis. Here, we use Xenopus laevis embryos to analyze the spatial and...
20.
Emergent cellular self-organization and mechanosensation initiate follicle pattern in the avian skin
Shyer A, Rodrigues A, Schroeder G, Kassianidou E, Kumar S, Harland R
Science
. 2017 Jul;
357(6353):811-815.
PMID: 28705989
The spacing of hair in mammals and feathers in birds is one of the most apparent morphological features of the skin. This pattern arises when uniform fields of progenitor cells...