Richard M Caprioli
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Explore the profile of Richard M Caprioli including associated specialties, affiliations and a list of published articles.
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301
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Recent Articles
1.
Cho S, Jones M, Meyer K, Anderson D, Chetyrkin S, Calcutt M, et al.
bioRxiv
. 2024 Oct;
PMID: 39464149
The qualities of antibody (Ab) responses provided by B lymphocytes and their plasma cell (PC) descendants are crucial facets of responses to vaccines and microbes. Metabolic processes and products regulate...
2.
Kruse A, Judd A, Gutierrez D, Allen J, Dufresne M, Farrow M, et al.
Anal Chem
. 2024 Oct;
96(42):16861-16870.
PMID: 39392310
Thermal denaturation (TD), known as antigen retrieval, heats tissue samples in a buffered solution to expose protein epitopes. Thermal denaturation of formalin-fixed paraffin-embedded samples enhances on-tissue tryptic digestion, increasing peptide...
3.
Good C, Butrico C, Colley M, Emmerson L, Gibson-Corley K, Cassat J, et al.
Cell Chem Biol
. 2024 Oct;
31(10):1852-1868.e5.
PMID: 39389064
Osteomyelitis occurs when Staphylococcus aureus invades the bone microenvironment, resulting in a bone marrow abscess with a spatially defined architecture of cells and biomolecules. Imaging mass spectrometry and microscopy are...
4.
Djambazova K, Gibson-Corley K, Freiberg J, Caprioli R, Skaar E, Spraggins J
J Am Soc Mass Spectrom
. 2024 Jul;
35(8):1692-1701.
PMID: 39052897
Gangliosides play important roles in innate and adaptive immunity. The high degree of structural heterogeneity results in significant variability in ganglioside expression patterns and greatly complicates linking structure and function....
5.
Zhang W, Patterson N, Verbeeck N, Moore J, Ly A, Caprioli R, et al.
PLoS One
. 2024 May;
19(5):e0304709.
PMID: 38820337
Imaging mass spectrometry (IMS) provides promising avenues to augment histopathological investigation with rich spatio-molecular information. We have previously developed a classification model to differentiate melanoma from nevi lesions based on...
6.
Sasiene Z, LeBrun E, Velappan N, Anderson A, Patterson N, Dufresne M, et al.
Analyst
. 2024 May;
149(13):3564-3574.
PMID: 38717518
Field-forward analytical technologies, such as portable mass spectrometry (MS), enable essential capabilities for real-time monitoring and point-of-care diagnostic applications. Significant and recent investments improving the features of miniaturized mass spectrometers...
7.
Klein D, Rivera E, Caprioli R, Spraggins J
Anal Chem
. 2024 Mar;
96(13):5065-5070.
PMID: 38517028
In this work, we demonstrate rapid, high spatial, and high spectral resolution imaging of intact proteins by matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) on a hybrid quadrupole-reflectron time-of-flight...
8.
Won Y, Jang B, Lee S, Reyzer M, Presentation K, Kim H, et al.
Gastroenterology
. 2024 Jan;
166(5):772-786.e14.
PMID: 38272100
Background & Aims: Gastric carcinogenesis develops within a sequential carcinogenic cascade from precancerous metaplasia to dysplasia and adenocarcinoma, and oncogenic gene activation can drive the process. Metabolic reprogramming is considered...
9.
Good C, Butrico C, Colley M, Gibson-Corley K, Cassat J, Spraggins J, et al.
bioRxiv
. 2023 Dec;
PMID: 38077019
Osteomyelitis occurs when invades the bone microenvironment, resulting in a bone marrow abscess with a spatially defined architecture of cells and biomolecules. Imaging mass spectrometry and microscopy are invaluable tools...
10.
Anderson D, Kotnala A, Messinger J, Patterson N, Spraggins J, Curcio C, et al.
Adv Exp Med Biol
. 2023 Jul;
1415:3-7.
PMID: 37440006
Pathologies of the retina are clinically visualized in vivo with OCT and ex vivo with immunohistochemistry. Although both techniques provide valuable information on prognosis and disease state, a comprehensive method...