Richard Kolesnick
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Explore the profile of Richard Kolesnick including associated specialties, affiliations and a list of published articles.
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90
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4623
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Recent Articles
1.
Mohamud Yusuf A, Borbor M, Hussner T, Weghs C, Kaltwasser B, Pillath-Eilers M, et al.
Cell Death Dis
. 2024 Sep;
15(9):650.
PMID: 39231943
Acid sphingomyelinase (ASM) inhibitors are widely used for the treatment of post-stroke depression. They promote neurological recovery in animal stroke models via neurorestorative effects. In a previous study, we found...
2.
Cheng J, Nagesh P, Feldman R, Shamu T, Zhang Z, Fuks Z, et al.
Cell Physiol Biochem
. 2024 Aug;
58(4):418-430.
PMID: 39172137
Background/aims: After 9/11, multiple government agencies instituted programs aimed at developing medical radiation countermeasures (MRCs) for two syndromes lethal within weeks of a limited nuclear attack; the hematopoietic-acute radiation syndrome...
3.
Das K, Keshava S, Kolesnick R, Pendurthi U, Rao L
J Thromb Haemost
. 2023 Nov;
22(2):441-454.
PMID: 37926194
Background: Factor VIIa induces the release of extracellular vesicles (EVs) from endothelial cells (EEVs). Factor VIIa-released EEVs are enriched with microRNA-10a (miR10a) and elicit miR10a-dependent cytoprotective responses. Objectives: To investigate...
4.
Das K, Keshava S, Mukherjee T, Wang J, Magisetty J, Kolesnick R, et al.
J Thromb Haemost
. 2023 Oct;
21(12):3414-3431.
PMID: 37875382
Background: Our recent studies showed that activated factor (F) VII (FVIIa) releases extracellular vesicles (EVs) from the endothelium. FVIIa-released EVs were found to be enriched with phosphatidylserine (PS) and contribute...
5.
Nagesh P, Monette S, Shamu T, Giralt S, St Jean S, Zhang Z, et al.
Int J Radiat Oncol Biol Phys
. 2023 Oct;
120(2):558-569.
PMID: 37815783
Purpose: After September 11, 2001, nuclear threat prompted government agencies to develop medical countermeasures to mitigate two syndromes, the hematopoietic-acute radiation syndrome (H-ARS) and the higher-dose gastrointestinal-acute radiation syndrome (GI-ARS),...
6.
Petrache I, Pujadas E, Ganju A, Serban K, Borowiec A, Babbs B, et al.
JCI Insight
. 2023 May;
8(10).
PMID: 37212278
The pathogenesis of the marked pulmonary microvasculature injury, a distinguishing feature of COVID-19 acute respiratory distress syndrome (COVID-ARDS), remains unclear. Implicated in the pathophysiology of diverse diseases characterized by endothelial...
7.
Li H, Kucharavy H, Hajj C, Zhao L, Hua G, Glass R, et al.
Cell Death Discov
. 2023 Mar;
9(1):99.
PMID: 36941253
No abstract available.
8.
Li H, Kucharavy H, Hajj C, Zhao L, Hua G, Glass R, et al.
Cell Death Discov
. 2023 Jan;
9(1):31.
PMID: 36697383
Previous studies show increased sensitivity of older mice (28-29 months) compared with young adult mice (3 months, possessing a mature immune system) to radiation-induced GI lethality. Age-dependent lethality was associated...
9.
Wang J, Keshava S, Das K, Kolesnick R, Jiang X, Pendurthi U, et al.
Arterioscler Thromb Vasc Biol
. 2022 Nov;
43(1):64-78.
PMID: 36412194
Background: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue factor) procoagulant activity. The current study was performed to investigate how alterations to sphingomyelin metabolic...
10.
Mohamud Yusuf A, Hagemann N, Zhang X, Zafar M, Hussner T, Bromkamp C, et al.
Basic Res Cardiol
. 2022 Aug;
117(1):43.
PMID: 36038749
Antidepressants have been reported to enhance stroke recovery independent of the presence of depressive symptoms. They have recently been proposed to exert their mood-stabilizing actions by inhibition of acid sphingomyelinase...