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Guoqiang Hua

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Articles 66
Citations 2559
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Recent Articles
1.
Mu P, Mo S, He X, Zhang H, Lv T, Xu R, et al.
J Exp Clin Cancer Res . 2025 Mar; 44(1):92. PMID: 40069844
Background: Radiotherapy (RT) is an essential treatment for colorectal cancer (CRC), yet the factors influencing radiosensitivity remain unclear. In the quest to enhance the therapeutic efficacy in CRC, the interplay...
2.
Hong F, Tan R, Wang T, Zhong N, Zhao H, Xu R, et al.
Cell Regen . 2025 Jan; 14(1):2. PMID: 39808364
Organoid technology provides a transformative approach to understand human physiology and pathology, offering valuable insights for scientific research and therapeutic development. Human gastric organoids, in particular, have gained significant interest...
3.
Hu X, Wu H, Hu K, Kang Y, Hua G, Cheng M, et al.
Clin Exp Metastasis . 2024 Dec; 42(1):8. PMID: 39739069
Patient-derived tumor organoids (PDTOs) models have been widely used to investigate the response of primary cancer tissues to anti-cancer agents. Nonetheless, only few case study tried to establish PDTOs and...
4.
Tan R, Hong F, Wang T, Zhong N, Zhao H, Xu R, et al.
Cell Regen . 2024 Dec; 13(1):33. PMID: 39729207
Gastric cancer is one of the most common malignancies with poor prognosis. The use of organoids to simulate gastric cancer has rapidly developed over the past several years. Patient-derived gastric...
5.
Ali E, Smaida R, Meyer M, Ou W, Li Z, Han Z, et al.
Stem Cell Res Ther . 2024 Jun; 15(1):185. PMID: 38926793
Cartilage, an important connective tissue, provides structural support to other body tissues, and serves as a cushion against impacts throughout the body. Found at the end of the bones, cartilage...
6.
Le H, Deforges J, Cutolo P, Lamarque A, Hua G, Lindner V, et al.
Front Immunol . 2024 May; 15:1379613. PMID: 38698850
Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including tumor-specific oncolysis and immunostimulatory properties. In this study, we...
7.
Le H, Deforges J, Hua G, Idoux-Gillet Y, Ponte C, Lindner V, et al.
iScience . 2023 Oct; 26(10):108094. PMID: 37860774
This work describes a patient-derived tumoroid model (PDTs) to support precision medicine in lung oncology. The use of human adipose tissue-derived microvasculature and patient-derived peripheral blood mononuclear cells (PBMCs) permits...
8.
Nounsi A, Seitlinger J, Ponte C, Demiselle J, Idoux-Gillet Y, Pencreach E, et al.
Biomedicines . 2023 Jul; 11(7). PMID: 37509464
Radiation therapy and platinum-based chemotherapy are common treatments for lung cancer patients. Several factors are considered for the low overall survival rate of lung cancer, such as the patient's physical...
9.
Ji S, Feng L, Fu Z, Wu G, Wu Y, Lin Y, et al.
Sci Transl Med . 2023 Jul; 15(706):eadg3358. PMID: 37494474
Organoid models have the potential to recapitulate the biological and pharmacotypic features of parental tumors. Nevertheless, integrative pharmaco-proteogenomics analysis for drug response features and biomarker investigation for precision therapy of...
10.
Vignes H, Smaida R, Conzatti G, Hua G, Benkirane-Jessel N
Trends Biotechnol . 2023 Jul; 41(12):1467-1470. PMID: 37423883
Reconstructing the meniscus is not currently possible due to its intricate and heterogeneous structure. In this forum, we first discuss the shortcomings of current clinical strategies in meniscus repair. Then,...