Richard J Kraus
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Explore the profile of Richard J Kraus including associated specialties, affiliations and a list of published articles.
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9
Citations
298
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Recent Articles
1.
Cordes B, Bilger A, Kraus R, Ward-Shaw E, Labott M, Lee S, et al.
Cancers (Basel)
. 2023 Mar;
15(6).
PMID: 36980731
Latent infection of Epstein-Barr virus (EBV) is associated with lymphoid and epithelial cell cancers, including 10% of gastric carcinomas. We previously reported that hypoxia inducible factor-1α (HIF-1α) induces EBV's latent-to-lytic...
2.
Kraus R, Cordes B, Sathiamoorthi S, Patel P, Yuan X, Iempridee T, et al.
J Virol
. 2020 Jul;
94(18).
PMID: 32641480
We previously reported that the cellular transcription factor hypoxia-inducible factor 1α (HIF-1α) binds a hypoxia response element (HRE) located within the promoter of Epstein-Barr virus's (EBV's) latent-lytic switch gene, Zp,...
3.
Kraus R, Yu X, Cordes B, Sathiamoorthi S, Iempridee T, Nawandar D, et al.
PLoS Pathog
. 2017 Jun;
13(6):e1006404.
PMID: 28617871
When confronted with poor oxygenation, cells adapt by activating survival signaling pathways, including the oxygen-sensitive transcriptional regulators called hypoxia-inducible factor alphas (HIF-αs). We report here that HIF-1α also regulates the...
4.
Yu X, McCarthy P, Lim H, Iempridee T, Kraus R, Gorlen D, et al.
J Virol
. 2011 Mar;
85(10):5081-90.
PMID: 21389123
The Epstein-Barr virus (EBV) BZLF1 gene encodes the immediate-early (IE) protein Zta, which plays a central role in regulating the switch between viral latency and lytic replication. A silencing element,...
5.
Vu E, Kraus R, Mertz J
Biochemistry
. 2007 Aug;
46(34):9795-804.
PMID: 17676930
We previously showed that estrogen-related receptor alpha1 (ERRalpha1) can compete with estrogen receptor alpha (ERalpha) for binding to estrogen response elements (EREs), repressing transcription in the mammary carcinoma cell line...
6.
Feng W, Kraus R, Dickerson S, Lim H, Jones R, Yu X, et al.
J Virol
. 2007 Jul;
81(18):10113-22.
PMID: 17626078
The induction of lytic infection has been proposed as a therapeutic strategy for treating Epstein-Barr virus (EBV)-positive malignancies. To succeed, efficient methods are needed for activating the EBV immediate-early (IE)...
7.
Ariazi E, Kraus R, Farrell M, Jordan V, Mertz J
Mol Cancer Res
. 2007 Jan;
5(1):71-85.
PMID: 17259347
We previously showed that (a) estrogen-related receptor alpha1 (ERRalpha1) down-modulates estrogen receptor (ER)-stimulated transcription in low ErbB2-expressing MCF-7 mammary carcinoma cells, and (b) ERRalpha and ErbB2 mRNA levels positively correlate...
8.
Kraus R, Perrigoue J, Mertz J
J Virol
. 2002 Dec;
77(1):199-207.
PMID: 12477825
Epstein-Barr virus (EBV) is a human herpesvirus capable of establishing a latent state in B lymphocytes. The product of the immediate-early BZLF1 gene, Zta, is a transcriptional transactivator essential for...
9.
Kraus R, Ariazi E, Farrell M, Mertz J
J Biol Chem
. 2002 May;
277(27):24826-34.
PMID: 11986328
The estrogen-related receptor alpha (ERRalpha) is an orphan member of the nuclear receptor superfamily. We show that the major isoform of the human ERRalpha gene, ERRalpha1, can sequence-specifically bind a...