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Richard F Ransom

Explore the profile of Richard F Ransom including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 428
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Recent Articles
1.
Hassan M, Shahzadi S, Ransom R, Kloczkowski A
Int J Mol Sci . 2023 Nov; 24(21). PMID: 37958579
Mushrooms are new potential sources of valuable medicines, long neglected because of difficulties experienced in their cultivation. There is a large variety of medicinal mushrooms which possess significant therapeutic properties...
2.
Agrawal S, Ransom R, Saraswathi S, Garcia-Gonzalo E, Webb A, Fernandez-Martinez J, et al.
J Clin Med . 2021 Feb; 10(3). PMID: 33540508
Glucocorticoid (GC) resistance complicates the treatment of ~10-20% of children with nephrotic syndrome (NS), yet the molecular basis for resistance remains unclear. We used RNAseq analysis and in silico algorithm-based...
3.
Gil de Rubio R, Ransom R, Malik S, Yule D, Anantharam A, Smrcka A
Sci Signal . 2018 Sep; 11(547). PMID: 30206135
Phospholipase C (PLC) enzymes hydrolyze the plasma membrane (PM) lipid phosphatidylinositol 4,5-bisphosphate (PI4,5P) to generate the second messengers inositol trisphosphate (IP) and diacylglycerol (DAG) in response to receptor activation in...
4.
Benndorf R, Gilmont R, Hirano S, Ransom R, Jungblut P, Bommer M, et al.
Cell Stress Chaperones . 2018 Mar; 23(5):813-826. PMID: 29542021
When analyzing small stress proteins of rat and human tissues by electrophoretic methods followed by western blotting, and using the anti-HspB1/anti-HspB5 antibody clone 8A7, we unexpectedly found a protein with...
5.
Ozaltin F, Li B, Rauhauser A, An S, Soylemezoglu O, Gonul I, et al.
J Am Soc Nephrol . 2013 Jan; 24(3):377-84. PMID: 23274426
Renal microangiopathies and membranoproliferative GN (MPGN) can manifest similar clinical presentations and histology, suggesting the possibility of a common underlying mechanism in some cases. Here, we performed homozygosity mapping and...
6.
Chittiprol S, Chen P, Petrovic-Djergovic D, Eichler T, Ransom R
Am J Physiol Renal Physiol . 2011 Jun; 301(3):F660-71. PMID: 21632959
The state-of-the-art cultured podocyte is conditionally immortalized by expression of a temperature-sensitive mutant of the SV40 large-T antigen. These cultures proliferate at 33°C and differentiate at 37°C into arborized cells...
7.
Pengal R, Guess A, Agrawal S, Manley J, Ransom R, Mourey R, et al.
Am J Physiol Renal Physiol . 2011 May; 301(3):F509-19. PMID: 21613416
While mitogen-activated protein kinase (MAPK) activation has been implicated in the pathogenesis of various glomerular diseases, including nephrotic syndrome (NS), its specific role in podocyte injury is not known. We...
8.
Guess A, Agrawal S, Wei C, Ransom R, Benndorf R, Smoyer W
Am J Physiol Renal Physiol . 2010 Jul; 299(4):F845-53. PMID: 20630936
Glucocorticoids (GC) are the primary therapy for idiopathic nephrotic syndrome (NS). Recent evidence has identified glomerular podocytes as a potential site of GC action in this disease. The objectives of...
9.
Reddy G, Kotlyarevska K, Ransom R, Menon R
Curr Opin Nephrol Hypertens . 2007 Dec; 17(1):32-6. PMID: 18090667
Purpose Of Review: Podocyte injury plays a key role in the development of diabetic nephropathy. This review discusses recent advances in our understanding of mechanisms of podocyte injury in diabetes...
10.
Reddy G, Pushpanathan M, Ransom R, Holzman L, Brosius 3rd F, Diakonova M, et al.
Endocrinology . 2007 Feb; 148(5):2045-55. PMID: 17272398
GH excess in both the human and transgenic animal models is characterized by significant changes in blood pressure and renal function. The GH/GH receptor (GHR) axis is also implicated in...