Richard E Jacob
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Explore the profile of Richard E Jacob including associated specialties, affiliations and a list of published articles.
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28
Citations
292
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Recent Articles
1.
Jacob R, Prowant M, Hutchinson C
Ultrasonics
. 2023 Oct;
136:107157.
PMID: 37806860
Ultrasonic inspection of cast austenitic stainless steel (CASS) in the nuclear industry is particularly challenging because of sound field scatter and attenuation caused by the coarse-grained microstructure. Modeling and simulation...
2.
Sun H, Ramuhalli P, Jacob R
Ultrasonics
. 2022 Oct;
127:106854.
PMID: 36215762
Recent years have seen a substantial increase in the application of machine learning (ML) for automated analysis of nondestructive examination (NDE) data. One of the applications of interest is the...
3.
Xi J, Si X, Kim J, Zhang Y, Jacob R, Kabilan S, et al.
Anat Rec (Hoboken)
. 2016 May;
299(7):853-68.
PMID: 27145450
The rabbit is commonly used as a laboratory animal for inhalation toxicology tests and detail knowledge of the rabbit airway morphometry is needed for outcome analysis or theoretical modeling. The...
4.
Colby S, Kabilan S, Jacob R, Kuprat A, Einstein D, Corley R
Inhal Toxicol
. 2016 Mar;
28(4):192-202.
PMID: 26986954
Context: Computational fluid dynamics (CFD) simulations of airflows coupled with physiologically based pharmacokinetic (PBPK) modeling of respiratory tissue doses of airborne materials have traditionally used either steady-state inhalation or a...
5.
Asgharian B, Price O, Kabilan S, Jacob R, Einstein D, Kuprat A, et al.
Inhal Toxicol
. 2016 Feb;
28(2):80-8.
PMID: 26895308
Despite using rabbits in several inhalation exposure experiments to study diseases such as anthrax, there is a lack of understanding regarding deposition characteristics and fate of inhaled particles (bio-aerosols and...
6.
Corley R, Kabilan S, Kuprat A, Carson J, Jacob R, Minard K, et al.
Toxicol Sci
. 2015 Apr;
146(1):65-88.
PMID: 25858911
Computational fluid dynamics (CFD) modeling is well suited for addressing species-specific anatomy and physiology in calculating respiratory tissue exposures to inhaled materials. In this study, we overcame prior CFD model...
7.
Jacob R, Lamm W, Einstein D, Krueger M, Glenny R, Corley R
Exp Lung Res
. 2014 Dec;
41(3):135-45.
PMID: 25513951
Purpose: Computer models for inhalation toxicology and drug-aerosol delivery studies rely on ventilation pattern inputs for predictions of particle deposition and vapor uptake. However, changes in lung mechanics due to...
8.
Miller F, Asgharian B, Schroeter J, Price O, Corley R, Einstein D, et al.
Inhal Toxicol
. 2014 Jul;
26(9):524-44.
PMID: 25055841
While inhalation toxicological studies of various compounds have been conducted using a number of different strains of rats, mechanistic dosimetry models have only had tracheobronchial (TB) structural data for Long-Evans...
9.
Jacob R, Carson J
BMC Med Imaging
. 2014 Jan;
14:1.
PMID: 24393332
Background: Assessing heterogeneity in lung images can be an important diagnosis tool. We present a novel and objective method for assessing lung damage in a rat model of emphysema. We...
10.
Jacob R, Murphy M, Creim J, Carson J
Acad Radiol
. 2013 Sep;
20(10):1264-71.
PMID: 24029058
Rationale And Objectives: To investigate the ability of variogram analysis of octree-decomposed computed tomography (CT) images and volume change maps to detect radiation-induced damage in rat lungs. Materials And Methods:...