Andrew P Kuprat
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Explore the profile of Andrew P Kuprat including associated specialties, affiliations and a list of published articles.
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21
Citations
211
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Recent Articles
1.
Sun Q, Zhang Y, Tian L, Tu J, Corley R, Kuprat A, et al.
Sci Total Environ
. 2024 Oct;
955:177028.
PMID: 39437906
The airflow and particle dynamics in adult nasal airways have been extensively investigated, but the impact of age-related anatomical changes in children and the elderly remains underexplored. This study systematically...
2.
Borojeni A, Gu W, Asgharian B, Price O, Kuprat A, Singh R, et al.
Pharmaceutics
. 2023 Jan;
15(1).
PMID: 36678786
The extrathoracic oral airway is not only a major mechanical barrier for pharmaceutical aerosols to reach the lung but also a major source of variability in lung deposition. Using computational...
3.
Corley R, Kuprat A, Suffield S, Kabilan S, Hinderliter P, Yugulis K, et al.
Toxicol Sci
. 2021 Jun;
182(2):243-259.
PMID: 34077545
Regulatory agencies are considering alternative approaches to assessing inhalation toxicity that utilizes in vitro studies with human cells and in silico modeling in lieu of additional animal studies. In support...
4.
Rod K, Um W, Colby S, Rockhold M, Strickland C, Han S, et al.
PLoS One
. 2019 Jan;
14(1):e0210741.
PMID: 30673742
Relative permeability is an important attribute influencing subsurface multiphase flow. Characterization of relative permeability is necessary to support activities such as carbon sequestration, geothermal energy production, and oil and gas...
5.
Kabilan S, Jung H, Kuprat A, Beck A, Varga T, Fernandez C, et al.
Environ Sci Technol
. 2016 May;
50(12):6180-8.
PMID: 27203125
X-ray microtomography (XMT) imaging combined with three-dimensional (3D) computational fluid dynamics (CFD) modeling technique was used to study the effect of geochemical and geomechanical processes on fracture permeability in composite...
6.
Colby S, Kabilan S, Jacob R, Kuprat A, Einstein D, Corley R
Inhal Toxicol
. 2016 Mar;
28(4):192-202.
PMID: 26986954
Context: Computational fluid dynamics (CFD) simulations of airflows coupled with physiologically based pharmacokinetic (PBPK) modeling of respiratory tissue doses of airborne materials have traditionally used either steady-state inhalation or a...
7.
Asgharian B, Price O, Kabilan S, Jacob R, Einstein D, Kuprat A, et al.
Inhal Toxicol
. 2016 Feb;
28(2):80-8.
PMID: 26895308
Despite using rabbits in several inhalation exposure experiments to study diseases such as anthrax, there is a lack of understanding regarding deposition characteristics and fate of inhaled particles (bio-aerosols and...
8.
Corley R, Kabilan S, Kuprat A, Carson J, Jacob R, Minard K, et al.
Toxicol Sci
. 2015 Apr;
146(1):65-88.
PMID: 25858911
Computational fluid dynamics (CFD) modeling is well suited for addressing species-specific anatomy and physiology in calculating respiratory tissue exposures to inhaled materials. In this study, we overcame prior CFD model...
9.
Thomas M, Marshall M, Miller E, Kuprat A, Kleese-van Dam K, Carson J
Annu Int Conf IEEE Eng Med Biol Soc
. 2015 Jan;
2014:3304-7.
PMID: 25570697
Understanding the structure of microbial biofilms and other complex microbial communities is now possible through x-ray microtomography imaging. Feature detection and image processing for this type of data focuses on...
10.
Thomas M, Heath B, Laskin J, Li D, Liu E, Hui K, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2013 Feb;
2012:5545-8.
PMID: 23367185
Mass Spectrometric Imaging (MSI) allows the generation of 2D ion density maps that help visualize molecules present in sections of tissues and cells. The combination of spatial resolution and mass...