Richard A Corley
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Explore the profile of Richard A Corley including associated specialties, affiliations and a list of published articles.
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60
Citations
952
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Recent Articles
1.
Stratmann H, Ma-Hock L, Tangermann S, Corley R
Front Toxicol
. 2023 Dec;
5:1258861.
PMID: 38115972
This case study aims to describe the dilemma faced when exposing rats to very high concentrations of fine, pulverulent materials for acute inhalation studies and to address the regulatory question...
2.
Borojeni A, Gu W, Asgharian B, Price O, Kuprat A, Singh R, et al.
Pharmaceutics
. 2023 Jan;
15(1).
PMID: 36678786
The extrathoracic oral airway is not only a major mechanical barrier for pharmaceutical aerosols to reach the lung but also a major source of variability in lung deposition. Using computational...
3.
Pande P, Madeen E, Williams D, Crowell S, Ognibene T, Turteltaub K, et al.
Toxicol Appl Pharmacol
. 2021 Dec;
438:115830.
PMID: 34933053
Dibenzo[def,p]chrysene (DBC) is an environmental polycyclic aromatic hydrocarbon (PAH) that causes tumors in mice and has been classified as a probable human carcinogen by the International Agency for Research on...
4.
Corley R, Kuprat A, Suffield S, Kabilan S, Hinderliter P, Yugulis K, et al.
Toxicol Sci
. 2021 Jun;
182(2):243-259.
PMID: 34077545
Regulatory agencies are considering alternative approaches to assessing inhalation toxicity that utilizes in vitro studies with human cells and in silico modeling in lieu of additional animal studies. In support...
5.
Hess B, Thomas D, Weber T, Hutchison J, Straub T, Bruckner-Lea C, et al.
PLoS One
. 2019 Jul;
14(7):e0219160.
PMID: 31260462
Inhalation of Bacillus anthracis spores can lead to an anthrax infection that can be fatal. Previously published mathematical models have extrapolated kinetic rates associated with bacterial growth in New Zealand...
6.
Ljungberg M, Sadi M, Wang Y, Aronow B, Xu Y, Kao R, et al.
Data Brief
. 2019 Jan;
22:365-372.
PMID: 30596133
This data is a curated collection of visual images of gene expression patterns from the pre- and post-natal mouse lung, accompanied by associated mRNA probe sequences and RNA-Seq expression profiles....
7.
Madeen E, Siddens L, Uesugi S, McQuistan T, Corley R, Smith J, et al.
Toxicol Appl Pharmacol
. 2018 Dec;
364:97-105.
PMID: 30582946
Benzo[a]pyrene (BaP), is a known human carcinogen (International Agency for Research on Cancer (IARC) class 1). The remarkable sensitivity (zepto-attomole C in biological samples) of accelerator mass spectrometry (AMS) makes...
8.
Zhou Y, Horowitz J, Naba A, Ambalavanan N, Atabai K, Balestrini J, et al.
Matrix Biol
. 2018 Mar;
73:77-104.
PMID: 29524630
The lung's unique extracellular matrix (ECM), while providing structural support for cells, is critical in the regulation of developmental organogenesis, homeostasis and injury-repair responses. The ECM, via biochemical or biomechanical...
9.
Moghieb A, Clair G, Mitchell H, Kitzmiller J, Zink E, Kim Y, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Mar;
315(1):L11-L24.
PMID: 29516783
Biochemical networks mediating normal lung morphogenesis and function have important implications for ameliorating morbidity and mortality in premature infants. Although several transcript-level studies have examined normal lung development, corresponding protein-level...
10.
Ardini-Poleske M, Clark R, Ansong C, Carson J, Corley R, Deutsch G, et al.
Am J Physiol Lung Cell Mol Physiol
. 2017 Aug;
313(5):L733-L740.
PMID: 28798251
The National Heart, Lung, and Blood Institute is funding an effort to create a molecular atlas of the developing lung (LungMAP) to serve as a research resource and public education...