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Richard D Klausner

Explore the profile of Richard D Klausner including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 3183
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Recent Articles
1.
Mathews D, Abernethy A, Chaikof E, Charo R, Daley G, Enriquez J, et al.
NAM Perspect . 2024 Jun; 2023. PMID: 38855738
No abstract available.
2.
Shigdel U, Lee S, Sowa M, Bowman B, Robison K, Zhou M, et al.
Proc Natl Acad Sci U S A . 2020 Jul; 117(29):17195-17203. PMID: 32606248
The vast majority of intracellular protein targets are refractory toward small-molecule therapeutic engagement, and additional therapeutic modalities are needed to overcome this deficiency. Here, the identification and characterization of a...
3.
Aravanis A, Lee M, Klausner R
Cell . 2017 Feb; 168(4):571-574. PMID: 28187279
Curative therapies are most successful when cancer is diagnosed and treated at an early stage. We advocate that technological advances in next-generation sequencing of circulating, tumor-derived nucleic acids hold promise...
4.
Riss J, Khanna C, Koo S, Chandramouli G, Yang H, Hu Y, et al.
Cancer Res . 2006 Jul; 66(14):7216-24. PMID: 16849569
Cancers have been described as wounds that do not heal, suggesting that the two share common features. By comparing microarray data from a model of renal regeneration and repair (RRR)...
5.
Klausner R
Nat Rev Drug Discov . 2004 Jun; 3(6):470. PMID: 15214330
No abstract available.
6.
Maranchie J, Afonso A, Albert P, Kalyandrug S, Phillips J, Zhou S, et al.
Hum Mutat . 2003 Dec; 23(1):40-6. PMID: 14695531
von Hippel Lindau disease (VHL) is an autosomal dominant familial cancer syndrome linked to alteration of the VHL tumor suppressor gene. Affected patients are predisposed to develop pheochromocytomas and cystic...
7.
Rosenwald A, Wright G, Leroy K, Yu X, Gaulard P, Gascoyne R, et al.
J Exp Med . 2003 Sep; 198(6):851-62. PMID: 12975453
Using current diagnostic criteria, primary mediastinal B cell lymphoma (PMBL) cannot be distinguished from other types of diffuse large B cell lymphoma (DLBCL) reliably. We used gene expression profiling to...
8.
Klausner R, Fauci A, Corey L, Nabel G, Gayle H, Berkley S, et al.
Science . 2003 Jun; 300(5628):2036-9. PMID: 12829768
A new collaborative model of research is needed to increase resources, to prioritize the R (ii) to increase the pace, reduce the overlap, and more systematically explore the elements of...
9.
Vasselli J, Shih J, Iyengar S, Maranchie J, Riss J, Worrell R, et al.
Proc Natl Acad Sci U S A . 2003 Jun; 100(12):6958-63. PMID: 12777628
To identify potential molecular determinants of tumor biology and possible clinical outcomes, global gene-expression patterns were analyzed in the primary tumors of patients with metastatic renal cell cancer by using...
10.
Rosenwald A, Wright G, Wiestner A, Chan W, Connors J, Campo E, et al.
Cancer Cell . 2003 Mar; 3(2):185-97. PMID: 12620412
We used gene expression profiling to establish a molecular diagnosis of mantle cell lymphoma (MCL), to elucidate its pathogenesis, and to predict the length of survival of these patients. An...