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Richard Bucala

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Articles 388
Citations 14079
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Recent Articles
11.
Ye S, Agalave N, Ma F, Mahmood D, Al-Grety A, Khoonsari P, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38674069
Bladder pain is a prominent symptom in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). We studied spinal mechanisms of bladder pain in mice using a model where repeated activation of intravesical Protease...
12.
Park H, Shin M, Shin J, Kim H, Kang B, Par-Young J, et al.
EBioMedicine . 2024 Apr; 103:105114. PMID: 38640835
Background: The innate immune cytokine interleukin (IL)-1 can affect T cell immunity, a critical factor in host defense. In a previous study, we identified a subset of human CD4 T...
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Solomon D, Kaplan M, Nigrovic P, Bucala R
Arthritis Rheumatol . 2024 Apr; 76(6):819-822. PMID: 38572586
No abstract available.
14.
Fan W, Wei B, Chen X, Zhang Y, Xiao P, Li K, et al.
Arthritis Res Ther . 2024 Jan; 26(1):31. PMID: 38243295
Objective: Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored...
15.
Wang H, Slotabec L, Didik S, Li Z, Leng L, Zhao B, et al.
Metabolism . 2024 Jan; 153:155792. PMID: 38232801
Macrophage migration inhibitory factor (MIF) is an innate cytokine that regulates both inflammatory and homeostatic responses. MIF is expressed by cardiomyocytes, where it exerts a protective action against ischemia-reperfusion (I/R)...
16.
Matejuk A, Benedek G, Bucala R, Matejuk S, Offner H, Vandenbark A
J Neuroinflammation . 2024 Jan; 21(1):8. PMID: 38178143
Progressive brain diseases create a huge social and economic burden on modern societies as a major cause of disability and death. Incidence of brain diseases has a significantly increasing trend...
17.
Young J, Park H, Kim M, Par-Young J, Bartlett H, Kim H, et al.
Immun Ageing . 2023 Dec; 20(1):71. PMID: 38042785
Background: Memory CD8 T cells expand with age. We previously demonstrated an age-associated expansion of effector memory (EM) CD8 T cells expressing low levels of IL-7 receptor alpha (IL-7Rα) and...
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Chen L, Li L, Cui D, Huang Y, Tong H, Zabihi H, et al.
Mol Metab . 2023 Nov; 79:101834. PMID: 37935315
Attenuation of adipose hormone sensitive lipase (HSL) may impair lipolysis and exacerbate obesity. We investigate the role of cytokine, macrophage migration inhibitory factor (MIF) in regulating adipose HSL and adipocyte...
20.
Fan W, Wei B, Chen X, Zhang Y, Xiao P, Li K, et al.
Res Sq . 2023 Oct; PMID: 37790522
Objective: Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored...