Jurgen Bernhagen
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Explore the profile of Jurgen Bernhagen including associated specialties, affiliations and a list of published articles.
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204
Citations
6627
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Recent Articles
1.
El Bounkari O, Zan C, Yang B, Ebert S, Wagner J, Bugar E, et al.
Nat Commun
. 2025 Mar;
16(1):2297.
PMID: 40055309
Atherosclerosis is the underlying cause of myocardial infarction and ischemic stroke. It is a lipid-triggered and cytokine/chemokine-driven arterial inflammatory condition. We identify D-dopachrome tautomerase/macrophage migration-inhibitory factor-2 (MIF-2), a paralog of...
2.
Asare Y, Yan G, Schlegl C, Prestel M, van der Vorst E, Teunissen A, et al.
Immunity
. 2025 Jan;
58(3):555-567.e9.
PMID: 39879983
Common genetic variants in a conserved cis-regulatory element (CRE) at histone deacetylase (HDAC)9 are a major risk factor for cardiovascular disease, including stroke and coronary artery disease. Given the consistency...
3.
Hornung S, Vogl D, Naltsas D, Volta B, Ballmann M, Marcon B, et al.
Angew Chem Int Ed Engl
. 2025 Jan;
:e202422834.
PMID: 39822034
Amyloid self-assembly of α-synuclein (αSyn) is linked to the pathogenesis of Parkinson's disease (PD). Type 2 diabetes (T2D) has recently emerged as a risk factor for PD. Cross-interactions between their...
4.
Konieczny M, Omarov M, Zhang L, Malik R, Richardson T, Baumeister S, et al.
Commun Biol
. 2025 Jan;
8(1):34.
PMID: 39794498
Circulating cytokines orchestrate immune reactions and are promising drug targets for immune-mediated and inflammatory diseases. Exploring the genetic architecture of circulating cytokine levels could yield key insights into causal mediators...
5.
Asare Y, Simsekyilmaz S, Kohncke J, Shagdarsuren G, Staudt M, Noels H, et al.
Thromb Haemost
. 2024 Oct;
PMID: 39366416
No abstract available.
6.
Zhang L, Woltering I, Holzner M, Brandhofer M, Schaefer C, Bushati G, et al.
Cell Mol Life Sci
. 2024 Jul;
81(1):296.
PMID: 38992165
Next to its classical role in MHC II-mediated antigen presentation, CD74 was identified as a high-affinity receptor for macrophage migration inhibitory factor (MIF), a pleiotropic cytokine and major determinant of...
7.
Windisch R, Soliman S, Hoffmann A, Chen-Wichmann L, Danese A, Vosberg S, et al.
Proc Natl Acad Sci U S A
. 2024 Jun;
121(25):e2312499121.
PMID: 38857395
Ex vivo expansion of human CD34+ hematopoietic stem and progenitor cells remains a challenge due to rapid differentiation after detachment from the bone marrow niche. In this study, we assessed...
8.
Breidung D, Megas I, Freytag D, Bernhagen J, Grieb G
Biomedicines
. 2024 Jan;
12(1).
PMID: 38275363
Macrophage migration inhibitory factor (MIF) and its homolog, D-dopachrome tautomerase (D-DT), are cytokines that play critical roles in the immune response to various infectious diseases. This review provides an overview...
9.
Crespo-Avilan G, Hernandez-Resendiz S, Ramachandra C, Ungureanu V, Lin Y, Lu S, et al.
Atherosclerosis
. 2024 Jan;
390:117450.
PMID: 38266625
Background And Aims: New treatments are needed to prevent neointimal hyperplasia that contributes to post-angioplasty and stent restenosis in patients with coronary artery disease (CAD) and peripheral arterial disease (PAD)....
10.
Prapiadou S, Zivkovic L, Thorand B, George M, van der Laan S, Malik R, et al.
Circulation
. 2023 Dec;
149(9):669-683.
PMID: 38152968
Background: Genetic and experimental studies support a causal involvement of IL-6 (interleukin-6) signaling in atheroprogression. Although trials targeting IL-6 signaling are underway, any benefits must be balanced against an impaired...