Richard A Franklin
Overview
Explore the profile of Richard A Franklin including associated specialties, affiliations and a list of published articles.
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48
Citations
2672
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Recent Articles
1.
McCubrey J, Meher A, Akula S, Abrams S, Steelman L, Lahair M, et al.
Aging (Albany NY)
. 2022 Apr;
14(8):3365-3386.
PMID: 35477123
TP53 is a master regulator of many signaling and apoptotic pathways involved in: aging, cell cycle progression, gene regulation, growth, apoptosis, cellular senescence, DNA repair, drug resistance, malignant transformation, metastasis,...
2.
Saxton P, Azariah S, Franklin R, Forster R, Werder S, Jenkins R, et al.
Sex Health
. 2018 Oct;
16(1):47-55.
PMID: 30274568
Methods: An open-label, single-arm treatment evaluation study design ('NZPrEP') was used. The settings were four publicly funded sexual health clinics in Auckland in 2017. The study population was 150 GBM...
3.
Ciuffreda L, Cesta Incani U, Steelman L, Abrams S, Falcone I, Del Curatolo A, et al.
Curr Pharm Des
. 2013 Oct;
20(24):3944-57.
PMID: 24138714
The RAS/RAF/MEK/ ERK and the PI3K/AKT/mTOR pathways govern fundamental physiological processes, such as cell proliferation, differentiation, metabolism, cytoskeleton reorganization and cell death and survival. Constitutive activation of these signal transduction...
4.
McCubrey J, Steelman L, Chappell W, Sun L, Davis N, Abrams S, et al.
Oncotarget
. 2013 Mar;
3(12):1505-21.
PMID: 23455493
Over the past few years, significant advances have occurred in both our understanding of the complexity of signal transduction pathways as well as the isolation of specific inhibitors which target...
5.
McCubrey J, Abrams S, Umezawa K, Cocco L, Martelli A, Franklin R, et al.
Adv Biol Regul
. 2013 Jan;
52(1):249-64.
PMID: 21930143
No abstract available.
6.
Chappell W, Abrams S, Franklin R, Lahair M, Montalto G, Cervello M, et al.
Cell Cycle
. 2012 Nov;
11(23):4447-61.
PMID: 23159854
Neutrophil gelatinase-associated lipocalin (NGAL, a.k.a Lnc2) is a member of the lipocalin family and has diverse roles. NGAL can stabilize matrix metalloproteinase-9 from autodegradation. NGAL is considered as a siderocalin...
7.
McCubrey J, Steelman L, Chappell W, Abrams S, Franklin R, Montalto G, et al.
Oncotarget
. 2012 Oct;
3(10):1068-111.
PMID: 23085539
The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Targeting these pathways is often complex and can result...
8.
Chappell W, Abrams S, Stadelman K, Lahair M, Franklin R, Cocco L, et al.
Adv Biol Regul
. 2012 Oct;
53(1):146-55.
PMID: 23073564
No abstract available.
9.
Steelman L, Navolanic P, Chappell W, Abrams S, Wong E, Martelli A, et al.
Cell Cycle
. 2011 Aug;
10(17):3003-15.
PMID: 21869603
Elucidating the response of breast cancer cells to chemotherapeutic and hormonal based drugs and radiation is clearly important as these are common treatment approaches. Signaling cascades often involved in chemo-,...
10.
Sokolosky M, Stadelman K, Chappell W, Abrams S, Martelli A, Stivala F, et al.
Oncotarget
. 2011 Jul;
2(7):538-50.
PMID: 21730367
Elucidating the response of breast cancer cells to chemotherapeutic and hormonal based drugs is clearly important as these are frequently used therapeutic approaches. A signaling pathway often involved in chemo-...