Richard A Baines
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Explore the profile of Richard A Baines including associated specialties, affiliations and a list of published articles.
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71
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1312
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Recent Articles
1.
Hunter I, Coulson B, Pettini T, Davies J, Parkin J, Landgraf M, et al.
Elife
. 2024 Jan;
12.
PMID: 38193543
Developing neural circuits are influenced by activity and are especially sensitive to changes in activity during critical periods (CPs) of development. Changes occurring during a CP often become 'locked in'...
2.
Karkali K, Vernon S, Baines R, Panayotou G, Martin-Blanco E
Nat Commun
. 2023 Dec;
14(1):8186.
PMID: 38081827
Central nervous system organogenesis is a complex process that obeys precise architectural rules. The impact that nervous system architecture may have on its functionality remains, however, relatively unexplored. To clarify...
3.
Sadeh T, Baines R, Black G, Manson F
Front Cell Dev Biol
. 2023 May;
11:1161548.
PMID: 37206923
Pathogenic, generally loss-of-function, variants in , encoding the Ca1.4α calcium channel, underlie congenital stationary night blindness type 2 (CSNB2), a rare inherited retinal disorder associated with visual disability. To establish...
4.
Dyson A, Ryan M, Garg S, Evans D, Baines R
eNeuro
. 2023 May;
10(5).
PMID: 37185294
Autism spectrum disorder (ASD) is a common neurodevelopmental condition for which there are no pharmacological therapies that effectively target its core symptomatology. Animal models of syndromic forms of ASD, such...
5.
Bradlaugh A, Fedele G, Munro A, Hansen C, Hares J, Patel S, et al.
Nature
. 2023 Mar;
615(7954):E27.
PMID: 36922600
No abstract available.
6.
Bradlaugh A, Fedele G, Munro A, Hansen C, Hares J, Patel S, et al.
Nature
. 2023 Feb;
615(7950):111-116.
PMID: 36813962
Many animals use Earth's magnetic field (also known as the geomagnetic field) for navigation. The favoured mechanism for magnetosensitivity involves a blue-light-activated electron-transfer reaction between flavin adenine dinucleotide (FAD) and...
7.
Coulson B, Hunter I, Doran S, Parkin J, Landgraf M, Baines R
Front Physiol
. 2022 Dec;
13:1073307.
PMID: 36531164
Critical periods are phases of heightened plasticity that occur during the development of neural networks. Beginning with pioneering work of Hubel and Wiesel, which identified a critical period for the...
8.
Dyson A, Ryan M, Garg S, Evans D, Baines R
J Neurosci
. 2022 Nov;
42(50):9450-9472.
PMID: 36344265
Autism spectrum disorder (ASD) is a neurodevelopmental condition in which the mechanisms underlying its core symptomatology are largely unknown. Studying animal models of monogenic syndromes associated with ASD, such as...
9.
Mattison K, Tossing G, Mulroe F, Simmons C, Butler K, Schreiber A, et al.
Brain
. 2022 Sep;
146(4):1357-1372.
PMID: 36074901
The vacuolar H+-ATPase is an enzymatic complex that functions in an ATP-dependent manner to pump protons across membranes and acidify organelles, thereby creating the proton/pH gradient required for membrane trafficking...
10.
Mulroe F, Lin W, MacKenzie-Gray Scott C, Aourz N, Fan Y, Coutts G, et al.
Dis Model Mech
. 2022 Sep;
15(10).
PMID: 36073607
Manipulating firing-rate neuronal homeostasis, which enables neurons to regulate their intrinsic excitability, offers an attractive opportunity to prevent seizures. However, to date, no drug-based interventions have been reported that manipulate...