Renata G Almeida
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Explore the profile of Renata G Almeida including associated specialties, affiliations and a list of published articles.
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14
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40
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Recent Articles
1.
Figueroa L, de Carvalho R, Almeida R, Paz E, Diogo E, Araujo M, et al.
RSC Med Chem
. 2024 Nov;
PMID: 39512946
The regioselective synthesis of functionalized naphthoquinones the formation and capture of naphthoquinonynes has been used to prepare trypanocidal compounds. The target compounds are functionalized on the aromatic ring, leaving the...
2.
Guimaraes E, Graca G, Diogo E, Almeida R, Pereira D, Araujo M, et al.
Chem Asian J
. 2024 Sep;
19(24):e202401050.
PMID: 39323072
An eco-friendly electrochemical halogenation of 2-amino-1,4-naphthoquinones has been developed. The new mild and energy efficient methodology comprises sustainable features like oxidant free and double role of the halogen source as...
3.
de Oliveira J, Abreu B, Paz E, Almeida R, Honorato J, Souza C, et al.
Chem Asian J
. 2024 Aug;
19(22):e202400757.
PMID: 39136413
Herein, we describe the Ru-catalyzed C-H alkenylation of 1,4-naphthoquinones (1,4-NQs), resulting in 1,4-naphthoquinoidal/SuFEx hybrids with moderate to good yields. This method provides a novel route for direct access to ethenesulfonyl-fluorinated...
4.
de Carvalho R, Wood J, Almeida R, Berry N, da Silva Junior E, Bower J
Angew Chem Int Ed Engl
. 2024 Mar;
63(18):e202400188.
PMID: 38445547
The first systematic exploration of the synthesis and reactivity of naphthoquinonynes is described. Routes to two regioisomeric Kobayashi-type naphthoquinonyne precursors have been developed, and the reactivity of the ensuing 6,7-...
5.
Santos L, Kronenberger T, Almeida R, Silva E, Rocha R, Oliveira J, et al.
J Chem Inf Model
. 2022 Aug;
62(24):6553-6573.
PMID: 35960688
The worldwide COVID-19 pandemic caused by the coronavirus SARS-CoV-2 urgently demands novel direct antiviral treatments. The main protease (M) and papain-like protease (PL) are attractive drug targets among coronaviruses due...
6.
Santos L, Kronenberger T, Almeida R, Silva E, Rocha R, Oliveira J, et al.
bioRxiv
. 2022 Jan;
PMID: 35018373
The worldwide COVID-19 pandemic caused by the coronavirus SARS-CoV-2 urgently demands novel direct antiviral treatments. The main protease (Mpro) and papain-like protease (PLpro) are attractive drug targets among coronaviruses due...
7.
Pena A, Almeida R, Campos J, Dos Santos H, da Silva Junior E, Jorio A
Phys Chem Chem Phys
. 2021 Dec;
24(2):1183-1190.
PMID: 34931633
This work reports a classification analysis method based on the vibrational Raman spectra of 38 quinones and related structures, spectrally ordering and classifying the compounds. The molecular systems are relevant...
8.
Lima D, Almeida R, Jardim G, Barbosa B, Santos A, Valenca W, et al.
RSC Med Chem
. 2021 Nov;
12(10):1709-1721.
PMID: 34778772
We report the synthesis of 47 new quinone-based derivatives click chemistry and their subsequent evaluation against cancer cell lines and the control L929 murine fibroblast cell line. These compounds combine...
9.
Pati S, Almeida R, da Silva Junior E, Namboothiri I
Beilstein J Org Chem
. 2021 Apr;
17:762-770.
PMID: 33828620
Desulfonylative alkylation of -tosyl-1,2,3-triazoles under metal-free conditions leading to β-triazolylenones is reported here. The present study encompasses the synthesis of triazoles with a new substitution pattern in a single step...
10.
Almeida R, Valenca W, Rosa L, De Simone C, de Castro S, Barbosa J, et al.
RSC Med Chem
. 2021 Jan;
11(10):1145-1160.
PMID: 33479619
-Quinones represent a special class of redox active compounds associated with a spectrum of pronounced biological activities, including selective cytotoxicity and antimicrobial actions. The modification of the quinone ring by...