Reisa A Sperling
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Explore the profile of Reisa A Sperling including associated specialties, affiliations and a list of published articles.
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371
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31952
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Recent Articles
1.
Zimmer J, Ardayfio P, Wang H, Khanna R, Evans C, Lu M, et al.
JAMA Neurol
. 2025 Mar;
PMID: 40063015
Importance: Amyloid-related imaging abnormalities (ARIA) are the major adverse event associated with amyloid-targeting immunotherapy. Identifying clinical features and individual risk factors for ARIA could facilitate effective prediction and prevention strategies....
2.
Coughlan G, Klinger H, Boyle R, Betthauser T, Binette A, Christenson L, et al.
JAMA Neurol
. 2025 Mar;
PMID: 40029638
Importance: Alzheimer disease (AD) predominates in females at almost twice the rate relative to males. Mounting evidence in adults without AD indicates that females exhibit higher tau deposition than age-matched...
3.
Kuhn E, Klinger H, Amariglio R, Wagner M, Jessen F, Duzel E, et al.
Alzheimers Dement
. 2025 Feb;
PMID: 39985404
Introduction: Specific features of subjective cognitive decline (SCD-plus) have been proposed to indicate an increased risk of preclinical Alzheimer's disease (AD). However, few studies have examined how these features relate...
4.
Wang L, Hu W, Dong F, Sheng C, Wu J, Han Y, et al.
Geroscience
. 2025 Jan;
PMID: 39888585
Brain network dynamics have been extensively explored in patients with subjective cognitive decline (SCD). However, these studies are susceptible to individual differences, scanning parameters, and other confounding factors. Therefore, how...
5.
Birkenbihl C, Cuppels M, Boyle R, Klinger H, Langford O, Coughlan G, et al.
Brain Inform
. 2025 Jan;
12(1):3.
PMID: 39871006
Cognitive resilience (CR) describes the phenomenon of individuals evading cognitive decline despite prominent Alzheimer's disease neuropathology. Operationalization and measurement of this latent construct is non-trivial as it cannot be directly...
6.
Wiels W, Oomens J, Engelborghs S, Baeken C, von Arnim C, Boada M, et al.
JAMA Psychiatry
. 2025 Jan;
82(3):296-310.
PMID: 39841452
Importance: Depressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association between depressive...
7.
Terao C, Wood Alexander M, Chalmers R, Boshmaf S, Paterson J, Black S, et al.
Alzheimers Dement (Amst)
. 2025 Jan;
17(1):e70052.
PMID: 39811702
Introduction: This study aimed to identify cognitive tests that optimally relate to tau positron emission tomography (PET) signal in the inferior temporal cortex (ITC), a neocortical region associated with early...
8.
Weizenbaum E, Hsieh S, Molinare C, Soberanes D, Christiano C, Viera A, et al.
J Prev Alzheimers Dis
. 2025 Jan;
12(3):100057.
PMID: 39809614
Background: The multi-day Boston Remote Assessment of Neurocognitive Health (BRANCH) is a remote, web-based assessment designed to capture the earliest cognitive changes in the preclinical stage of Alzheimer's disease (AD)....
9.
Wolk D, Nelson P, Apostolova L, Arfanakis K, Boyle P, Carlsson C, et al.
Alzheimers Dement
. 2025 Jan;
21(1):e14202.
PMID: 39807681
Limbic predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is highly prevalent in late life and a common co-pathology with Alzheimer's disease neuropathologic change (ADNC). LATE-NC is a slowly progressive, amnestic...
10.
Jutten R, Soberanes D, Molinare C, Hsieh S, Farrell M, Schultz A, et al.
NPJ Digit Med
. 2025 Jan;
8(1):24.
PMID: 39806194
Remote, digital cognitive testing on an individual's own device provides the opportunity to deploy previously understudied but promising cognitive paradigms in preclinical Alzheimer's disease (AD). The Boston Remote Assessment for...