Aaron P Schultz
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Explore the profile of Aaron P Schultz including associated specialties, affiliations and a list of published articles.
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113
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5606
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Recent Articles
1.
Coughlan G, Klinger H, Boyle R, Betthauser T, Binette A, Christenson L, et al.
JAMA Neurol
. 2025 Mar;
PMID: 40029638
Importance: Alzheimer disease (AD) predominates in females at almost twice the rate relative to males. Mounting evidence in adults without AD indicates that females exhibit higher tau deposition than age-matched...
2.
Birkenbihl C, Cuppels M, Boyle R, Klinger H, Langford O, Coughlan G, et al.
Brain Inform
. 2025 Jan;
12(1):3.
PMID: 39871006
Cognitive resilience (CR) describes the phenomenon of individuals evading cognitive decline despite prominent Alzheimer's disease neuropathology. Operationalization and measurement of this latent construct is non-trivial as it cannot be directly...
3.
Klinger H, Healy B, Hanseeuw B, Jones R, Boyle R, Townsend D, et al.
Alzheimers Dement
. 2024 Oct;
20(12):8728-8738.
PMID: 39470175
Introduction: While the influence of cross-sectional β-amyloid (Aβ) on longitudinal changes in cognition is well established, longitudinal change-on-change between Aβ and cognition is less explored. Methods: A series of bivariate...
4.
Birkenbihl C, Cuppels M, Boyle R, Klinger H, Langford O, Coughlan G, et al.
medRxiv
. 2024 Sep;
PMID: 39228697
Cognitive resilience describes the phenomenon of individuals evading cognitive decline despite prominent Alzheimer's disease neuropathology. Operationalization and measurement of this latent construct is non-trivial as it cannot be directly observed....
5.
Stankeviciute L, Chhatwal J, Levin R, Pinilla V, Schultz A, Redline S, et al.
Alzheimers Dement (Amst)
. 2024 Jul;
16(3):e12616.
PMID: 39077684
Introduction: Sleep is crucial for memory consolidation and the clearance of toxic proteins associated with Alzheimer's disease (AD). We examined the association between sleep characteristics and imaging biomarkers of early...
6.
Schultz S, Liu L, Schultz A, Fitzpatrick C, Levin R, Bellier J, et al.
Lancet Neurol
. 2024 Jul;
23(9):913-924.
PMID: 39074479
Background: Genetic variants that cause autosomal dominant Alzheimer's disease are highly penetrant but vary substantially regarding age at symptom onset (AAO), rates of cognitive decline, and biomarker changes. Most pathogenic...
7.
Farrell M, Thibault E, Becker J, Price J, Healy B, Hanseeuw B, et al.
Alzheimers Dement
. 2024 Jul;
20(8):5434-5449.
PMID: 38988055
Introduction: Spatial extent-based measures of how far amyloid beta (Aβ) has spread throughout the neocortex may be more sensitive than traditional Aβ-positron emission tomography (PET) measures of Aβ level for...
8.
Boyle R, Townsend D, Klinger H, Scanlon C, Yuan Z, Coughlan G, et al.
Alzheimers Res Ther
. 2024 Jul;
16(1):148.
PMID: 38961512
Background: Leveraging Alzheimer's disease (AD) imaging biomarkers and longitudinal cognitive data may allow us to establish evidence of cognitive resilience (CR) to AD pathology in-vivo. Here, we applied latent class...
9.
Dubbelman M, Diez I, Gonzalez C, Amariglio R, Becker J, Chhatwal J, et al.
Front Aging Neurosci
. 2024 Jun;
16:1420290.
PMID: 38934017
Background: Changes in everyday functioning constitute a clinically meaningful outcome, even in the early stages of Alzheimer's disease. Performance-based assessments of everyday functioning might help uncover these early changes. We...
10.
Engels-Dominguez N, Koops E, Hsieh S, Wiklund E, Schultz A, Riphagen J, et al.
Alzheimers Res Ther
. 2024 Jun;
16(1):129.
PMID: 38886798
Background: Autopsy work indicates that the widely-projecting noradrenergic pontine locus coeruleus (LC) is among the earliest regions to accumulate hyperphosphorylated tau, a neuropathological Alzheimer's disease (AD) hallmark. This early tau...