Reinhold Wintersteiger
Overview
Explore the profile of Reinhold Wintersteiger including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
175
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Recent Articles
1.
Greilberger J, Stiegler P, Greilberger M, Wintersteiger R
Cells
. 2024 Jun;
13(11.
PMID: 38891069
Methods: Jurkat and MTC-SK cells were cultured in the absence or presence of varying concentrations (0-500 µg/mL) of NASeLM and NALM solutions. After 0, 24, 48, and 72 h, mitochondrial...
2.
Greilberger J, Erlbacher K, Stiegler P, Wintersteiger R, Herwig R
Curr Issues Mol Biol
. 2023 Aug;
45(8):6503-6525.
PMID: 37623229
Background: Carbonylated proteins (CPs) serve as specific indicators of increased reactive oxygen and nitrogen species (RONS) production in cancer cells, attributed to the dysregulated mitochondrial energy metabolism known as the...
3.
Greilberger J, Herwig R, Kacar M, Brajshori N, Feigl G, Stiegler P, et al.
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012295
Background: We recently showed that a combined solution containing alpha-ketoglutarate (aKG) and 5-hydroxymethyl-furfural (5-HMF) has a solid antitumoral effect on the Jurkat cell line due to the fact of its...
4.
Greilberger J, Herwig R, Greilberger M, Stiegler P, Wintersteiger R
Antioxidants (Basel)
. 2021 Nov;
10(11).
PMID: 34829675
We have recently shown that a combined solution containing alpha-ketoglutarate (aKG) and 5-hydroxymethyl-furfural (5-HMF) might have anti-tumoral potential due to its antioxidative activities. The question arises if these substances have...
5.
Woyke S, Mair N, Ortner A, Haller T, Ronzani M, Rugg C, et al.
Nutrients
. 2021 Oct;
13(10).
PMID: 34684449
5-Hydroxymethylfurfural (5-HMF) is known to increase hemoglobin oxygen affinity (Hb-O affinity) and to induce a left shift of the oxygen dissociation curve (ODC). It is under investigation as a therapeutic...
6.
Greilberger J, Greilberger M, Wintersteiger R, Zangger K, Herwig R
Antioxidants (Basel)
. 2021 Sep;
10(9).
PMID: 34573133
The generation of peroxynitrite (ONOO) is associated with several diseases, including atherosclerosis, hypertension, neurodegeneration, cancer, inflammation, and sepsis. Alpha-ketoglutarate (αKG) is a known potential highly antioxidative agent for radical oxidative...
7.
Andra M, Russ M, Jauk S, Lamacie M, Lang I, Arnold R, et al.
Oxid Med Cell Longev
. 2020 Aug;
2020:2862631.
PMID: 32802261
As progressive organ shortage in cardiac transplantation demands extension of donor criteria, effort is needed to optimize graft survival. Reactive oxygen and nitrogen species, generated during organ procurement, transplantation, and...
8.
Russ M, Jauk S, Wintersteiger R, Andra M, Brcic I, Ortner A
Mol Cell Biochem
. 2019 Jul;
461(1-2):73-80.
PMID: 31342300
A multi-component solution, containing α-ketoglutaric acid (α-KG), 5-hydroxymethylfurfural (5-HMF), N-acetyl-seleno-L-methionine (NASeLM), and N-acetyl-L-methionine (NALM) as active ingredients, has been tested considering its supposed antioxidative effect with respect to heart transplantations....
9.
Russ M, Hauser S, Wintersteiger R, Greilberger J, Andra M, Ortner A
J Fluoresc
. 2015 Oct;
26(1):81-6.
PMID: 26452351
Angiotensin-(1-7) is an important active component in the renin-angiotensin-system. Due to its cardio protective effects it is now under investigation in combination with antioxidants as a reperfusion solution. The combination...
10.
Donnarumma F, Wintersteiger R, Schober M, Greilberger J, Matzi V, Maier A, et al.
Anal Sci
. 2013 Dec;
29(12):1177-82.
PMID: 24334984
Alpha-ketoglutaric acid (KG) and hydroxymethylfurfural (HMF) are currently being investigated in clinical trials as an approach in targeted cancer therapy. Hence, a method for the simultaneous determination of KG and...