Peter Sedlmayr
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Explore the profile of Peter Sedlmayr including associated specialties, affiliations and a list of published articles.
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41
Citations
669
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Recent Articles
1.
Broekhuizen M, Klein T, Hitzerd E, de Rijke Y, Schoenmakers S, Sedlmayr P, et al.
Hypertension
. 2020 Jun;
76(1):184-194.
PMID: 32475317
l-tryptophan induces IDO (indoleamine 2,3-dioxygenase) 1-dependent vasodilation. IDO1 is expressed in placental endothelial cells and downregulated in preeclampsia. Hypothesizing that this may contribute to diminished placental perfusion, we studied l-tryptophan-induced...
2.
Chen S, Tauber G, Langsenlehner T, Schmolzer L, Potscher M, Riethdorf S, et al.
Cancers (Basel)
. 2019 Jul;
11(7).
PMID: 31277254
High-risk non-metastatic prostate cancer (PCa) has the potential to progress into lethal disease. Treatment options are manifold but, given a lack of surrogate biomarkers, it remains unclear which treatment offers...
3.
Chen S, El-Heliebi A, Schmid J, Kashofer K, Czyz Z, Polzer B, et al.
J Vis Exp
. 2018 Jun;
(135).
PMID: 29863657
Rare target cells can be isolated from a high background of non-target cells using antibodies specific for surface proteins of target cells. A recently developed method uses a medical wire...
4.
Zardoya-Laguardia P, Blaschitz A, Hirschmugl B, Lang I, Herzog S, Nikitina L, et al.
Sci Rep
. 2018 Apr;
8(1):5488.
PMID: 29615752
Indoleamine 2,3-dioxygenase-1 (IDO1) mediates the degradation of L-tryptophan (L-Trp) and is constitutively expressed in the chorionic vascular endothelium of the human placenta with highest levels in the microvasculature. Given that...
5.
El-Heliebi A, Hille C, Laxman N, Svedlund J, Haudum C, Ercan E, et al.
Clin Chem
. 2018 Jan;
64(3):536-546.
PMID: 29301749
Background: Liquid biopsies can be used in castration-resistant prostate cancer (CRPC) to detect androgen receptor splice variant 7 (AR-V7), a splicing product of the androgen receptor. Patients with AR-V7-positive circulating...
6.
Markou A, Lazaridou M, Paraskevopoulos P, Chen S, Swierczewska M, Budna J, et al.
Clin Chem
. 2017 Nov;
64(2):297-306.
PMID: 29122836
Background: Molecular characterization of circulating tumor cells (CTCs) is important for selecting patients for targeted treatments. We present, for the first time, results on gene expression profiling of CTCs isolated...
7.
Stahlberg A, El-Heliebi A, Sedlmayr P, Kroneis T
Brief Funct Genomics
. 2017 Oct;
17(4):255-264.
PMID: 29028900
The presence of microchimeric cells is known for >100 years and well documented since decades. Earlier, microchimeric cells were mainly used for cell-based non-invasive prenatal diagnostics during early pregnancy. Microchimeric...
8.
El-Heliebi A, Kashofer K, Fuchs J, Jahn S, Viertler C, Matak A, et al.
Histochem Cell Biol
. 2017 Mar;
148(2):105-115.
PMID: 28321501
Tumor heterogeneity is considered a major cause for therapy resistance in colorectal cancer. Sub-populations of cells with different genetic alterations may exist in spatially distinct areas. Upon therapy, resistant sub-clones...
9.
Chen S, El-Heliebi A, Tauber G, Langsenlehner T, Potscher M, Kashofer K, et al.
Sci Rep
. 2017 Feb;
7:43424.
PMID: 28233867
Enumeration and especially molecular characterization of circulating tumour cells (CTCs) holds great promise for cancer management. We tested a modified type of an in vivo enrichment device (Catch&Release) for its...
10.
Holland O, Kroneis T, El-Heliebi A, McDowell-Hook M, Stone P, Sedlmayr P, et al.
Fetal Diagn Ther
. 2016 Apr;
41(1):32-40.
PMID: 27115893
Objectives: A key problem in prenatal screening using extra-embryonic cells is the feasibility of extracting usable DNA from a small number of cells. Syncytial nuclear aggregates (SNAs) are multinucleated structures...