Regalla Kumarswamy
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Explore the profile of Regalla Kumarswamy including associated specialties, affiliations and a list of published articles.
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28
Citations
2404
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Recent Articles
1.
Nanda D, Pant P, Machha P, Sowpati D, Kumarswamy R
Front Mol Biosci
. 2024 Jan;
10:1263913.
PMID: 38178867
β-adrenergic stimulation using β-agonists such as isoproterenol has been routinely used to induce cardiac fibrosis in experimental animal models. Although transcriptome changes in surgical models of cardiac fibrosis such as...
2.
Pant P, Kumarswamy R
RNA Biol
. 2023 Dec;
21(1):1-9.
PMID: 38105541
Understanding RNA-protein interactions is crucial for deciphering the cellular functions and molecular mechanisms of regulatory RNAs. Consequently, there is a constant need to develop innovative and cost-effective methods to uncover...
3.
Bharadhwaj R, Kumarswamy R
Am J Physiol Cell Physiol
. 2023 Aug;
325(4):C940-C950.
PMID: 37642238
Abdominal aortic aneurysms (AAAs) are asymptomatic vascular diseases that have life-threatening outcomes. Smooth muscle cell (SMC) dysfunction plays an important role in AAA development. The contribution of non-coding genome, specifically...
4.
Sassi Y, Avramopoulos P, Ramanujam D, Gruter L, Werfel S, Giosele S, et al.
Nat Commun
. 2017 Nov;
8(1):1614.
PMID: 29158499
Chronic cardiac stress induces pathologic hypertrophy and fibrosis of the myocardium. The microRNA-29 (miR-29) family has been found to prevent excess collagen expression in various organs, particularly through its function...
5.
Beermann J, Kirste D, Iwanov K, Lu D, Kleemiss F, Kumarswamy R, et al.
Cell Death Differ
. 2017 Nov;
25(2):307-318.
PMID: 29099486
The mammalian cell cycle is a complex and tightly controlled event. Myriads of different control mechanisms are involved in its regulation. Long non-coding RNAs (lncRNA) have emerged as important regulators...
6.
Viereck J, Kumarswamy R, Foinquinos A, Xiao K, Avramopoulos P, Kunz M, et al.
Sci Transl Med
. 2016 Feb;
8(326):326ra22.
PMID: 26888430
Recent studies highlighted long noncoding RNAs (lncRNAs) to play an important role in cardiac development. However, understanding of lncRNAs in cardiac diseases is still limited. Global lncRNA expression profiling indicated...
7.
Lorenzen J, Schauerte C, Hubner A, Kolling M, Martino F, Scherf K, et al.
Eur Heart J
. 2015 Apr;
36(32):2184-96.
PMID: 25898844
Aims: Osteopontin (OPN) is a multifunctional cytokine critically involved in cardiac fibrosis. However, the underlying mechanisms are unresolved. Non-coding RNAs are powerful regulators of gene expression and thus might mediate...
8.
Dangwal S, Stratmann B, Bang C, Lorenzen J, Kumarswamy R, Fiedler J, et al.
Arterioscler Thromb Vasc Biol
. 2015 Mar;
35(6):1480-8.
PMID: 25814674
Objective: MicroRNAs (miRNA/miR) are stably present in body fluids and are increasingly explored as disease biomarkers. Here, we investigated influence of impaired wound healing on the plasma miRNA signature and...
9.
Viereck J, Kumarswamy R, Thum T
Circulation
. 2015 Mar;
131(14):1236-8.
PMID: 25739400
No abstract available.
10.
Lorenzen J, Schauerte C, Kielstein J, Hubner A, Martino F, Fiedler J, et al.
Clin Chem
. 2014 Oct;
61(1):191-201.
PMID: 25294924
Background: Long noncoding RNAs (lncRNAs) are novel intracellular noncoding ribonucleotides regulating gene expression. Intriguingly, these RNA transcripts are detectable and stable in the blood of patients with cancer and cardiovascular...