Johan M Lorenzen
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Explore the profile of Johan M Lorenzen including associated specialties, affiliations and a list of published articles.
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53
Citations
1958
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Recent Articles
1.
van Zonneveld A, Kolling M, Bijkerk R, Lorenzen J
Nat Rev Nephrol
. 2021 Aug;
17(12):814-826.
PMID: 34381199
Circular RNAs (circRNAs) are a class of endogenously expressed regulatory RNAs with a single-stranded circular structure. They are generated by back splicing and their expression can be tightly regulated by...
2.
Bonani M, Seeger H, Weber N, Lorenzen J, Wuthrich R, Kistler A
Kidney Blood Press Res
. 2021 Jun;
46(3):310-322.
PMID: 34077930
Introduction: Kidney biopsy remains the gold standard for the diagnosis of most renal diseases. A major obstacle to performing a biopsy is safety concerns. However, many safety measures are not...
3.
Pokidysheva E, Seeger H, Pedchenko V, Chetyrkin S, Bergmann C, Abrahamson D, et al.
J Biol Chem
. 2021 Mar;
296:100590.
PMID: 33774048
Diseases of the glomerular basement membrane (GBM), such as Goodpasture's disease (GP) and Alport syndrome (AS), are a major cause of chronic kidney failure and an unmet medical need. Collagen...
4.
Kielstein J, Heisterkamp M, Jing J, Nadal J, Schmid M, Kronenberg F, et al.
Clin Kidney J
. 2021 Feb;
14(1):277-283.
PMID: 33564429
Background: Despite a plethora of studies on the effect of urate-lowering therapy (ULT) in patients with chronic kidney disease (CKD), current guidelines on the treatment of hyperuricaemia and gout vary,...
5.
Nowak A, Haddad G, Kistler A, Nlandu-Khodo S, Beuschlein F, Wuthrich R, et al.
J Med Genet
. 2021 Feb;
59(3):279-286.
PMID: 33547137
Background: Fabry disease is a rare X-linked lysosomal storage disease caused by mutations in the galactosidase α gene. Deficient activity of α-galactosidase A leads to glycosphingolipid accumulations in multiple organs....
6.
Haddad G, Kolling M, Wegmann U, Dettling A, Seeger H, Schmitt R, et al.
J Am Soc Nephrol
. 2021 Jan;
32(2):323-341.
PMID: 33478972
Background: Renal ischemia-reperfusion (I/R) injury is a major cause of AKI. Noncoding RNAs are intricately involved in the pathophysiology of this form of AKI. Transcription of hypoxia-induced, long noncoding RNA...
7.
Haddad G, Lorenzen J, Ma H, de Haan N, Seeger H, Zaghrini C, et al.
J Clin Invest
. 2020 Dec;
131(5).
PMID: 33351779
Primary membranous nephropathy (pMN) is a leading cause of nephrotic syndrome in adults. In most cases, this autoimmune kidney disease is associated with autoantibodies against the M-type phospholipase A2 receptor...
8.
Brandenburger T, Lorenzen J
Front Pharmacol
. 2020 Jun;
11:657.
PMID: 32477132
During hospital stay, about 20% of adult patients experience an episode of acute kidney injury (AKI), which is characterized by a rapid decrease in kidney function. Diagnostic tools regarding early...
9.
10.
Kolling M, Haddad G, Wegmann U, Kistler A, Bosakova A, Seeger H, et al.
Clin Chem
. 2019 Aug;
65(10):1287-1294.
PMID: 31371281
Background: Circular RNAs (circRNAs) have recently been described as novel noncoding regulators of gene expression. They are detectable in the blood of patients with acute kidney injury. We tested whether...