Reem M Hashem
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Explore the profile of Reem M Hashem including associated specialties, affiliations and a list of published articles.
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17
Citations
267
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Recent Articles
1.
Kandeil M, Hashem R, Mahmoud M, Hetta M, Tohamy M
J Food Biochem
. 2019 Oct;
43(12):e13076.
PMID: 31608477
Endoplasmic reticulum (ER) stress was reported to play a major role in non-alcoholic fatty liver disease (NAFLD) induction and progression. Here, we study the effect of Zingiber officinale and omega-3...
2.
Hashem R, Rashed L, Hassanin K, Hetta M, Ahmed A
Biomed Pharmacother
. 2017 Jan;
88:293-301.
PMID: 28113081
Objectives: Adenosine monophosphate (AMP)-activated protein kinase (AMPK) plays a central role in metabolic homeostasis and regulation of inflammatory responses through attenuation of nuclear factor kappa-B (NF-κB), Thus AMPK may be...
3.
Hashem R, Hassanin K, Rashed L, Mahmoud M, Hassan M
Exp Biol Med (Maywood)
. 2016 Mar;
241(11):1250-7.
PMID: 26941058
Apoptosis signal-regulating kinase 1 (ASK1), a redox-sensor mitogen-activated protein kinase kinase kinase (MAPKKK) that activates p38 MAPK pathways in oxidative stress-induced hepatotoxicity in D-galactosamine/lipopolysaccharide (D-GalN/LPS) model, is a key central...
4.
Hashem R, Mohamed R, Abo-El-matty D
Nutrition
. 2016 Jan;
32(4):478-85.
PMID: 26732833
Objectives: Tumor necrosis factor α (TNF-α) is implicated in the pathophysiology of renal obstruction through its interactions with two TNF-α receptors: TNFR1 and TNFR2. Activation of TNFR1 leads to the...
5.
Hussein R, Hashem R, Rashed L
Front Mol Neurosci
. 2015 Aug;
8:40.
PMID: 26283911
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the accumulation and aggregation of extracellular amyloid β (Aβ) peptides and intracellular aggregation of hyper-phosphorylated tau protein. Recent evidence indicates...
6.
Hashem R, Rashd L, Hashem K, Soliman H
Biomed Pharmacother
. 2015 Jul;
73:80-6.
PMID: 26211586
Translocation of the master regulator of antioxidant-response element-driven antioxidant gene, nuclear factor erythroid 2 (Nrf-2) from the cytoplasm into the nucleus and triggering the transcription of hemoxygenase-1 (HO-1) to counteract...
7.
Mansson C, Arosio P, Hussein R, Kampinga H, Hashem R, Boelens W, et al.
J Biol Chem
. 2014 Sep;
289(45):31066-76.
PMID: 25217638
The human molecular chaperone protein DNAJB6 was recently found to inhibit the formation of amyloid fibrils from polyglutamine peptides associated with neurodegenerative disorders such as Huntington disease. We show in...
8.
Motawi T, Hamed M, Hashem R, Shabana M, Ahmed Y
Z Naturforsch C J Biosci
. 2012 Apr;
67(1-2):47-57.
PMID: 22486041
The protective and therapeutic effects of Argyreia speciosa Sweet (Convolvulaceae) against ethanol-induced gastric ulcer in rats were evaluated. Ethanolic and water extracts of the aerial plant parts (200 mg/kg body...
9.
Rashed L, Hashem R, Soliman H
Biomed Pharmacother
. 2011 Oct;
65(7):474-80.
PMID: 21993003
Oxidative stress significantly contributes to cisplatin (CP)-associated cytotoxicity, and use of antioxidants could counteract such cytotoxic effects of CP. The major biochemical pathway for reactive oxygen species (ROS) formation proceeds...
10.
Motawi T, Hamed M, Shabana M, Hashem R, Naser A
Nutr Metab (Lond)
. 2011 Jun;
8:40.
PMID: 21689445
Background/objective: Zingiber officinale Roscoe (ginger) (Zingiberaceae) has been cultivated for thousands of years both as a spice and for medicinal purposes. Ginger rhizomes successive extracts (petroleum ether, chloroform and ethanol)...