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Rebecca Batorsky

Explore the profile of Rebecca Batorsky including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 315
Followers 0
Related Specialties
Biology
Molecular Biology
Biochemistry
Top 10 Co-Authors
Michael T Chin
Gayani Perera
Paul Kellam
Benjamin A Devlin
Alexander Poltorak
Alexis M Ceasrine
Martin S Maron
David Jetton
Andrea G Edlow
Philip J R Goulder
Published In
Retrovirology
Cell Rep
Int J Mol Sci
J Am Heart Assoc
Proc Natl Acad Sci U S A
Affiliations
Soon will be listed here.
Recent Articles
11.
Bioengineered models of Parkinson's disease using patient-derived dopaminergic neurons exhibit distinct biological profiles in a 3D microenvironment
Fiore N, Ganat Y, Devkota K, Batorsky R, Lei M, Lee K, et al.
Cell Mol Life Sci . 2022 Jan; 79(2):78. PMID: 35044538
Three-dimensional (3D) in vitro culture systems using human induced pluripotent stem cells (hiPSCs) are useful tools to model neurodegenerative disease biology in physiologically relevant microenvironments. Though many successful biomaterials-based 3D...
12.
Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient
Brener J, Gall A, Hurst J, Batorsky R, Lavandier N, Chen F, et al.
Retrovirology . 2018 Jan; 15(1):7. PMID: 29338738
Background: The factors determining differential HIV disease outcome among individuals expressing protective HLA alleles such as HLA-B*27:05 and HLA-B*57:01 remain unknown. We here analyse two HIV-infected subjects expressing both HLA-B*27:05...
13.
Orthogonal NGS for High Throughput Clinical Diagnostics
Chennagiri N, White E, Frieden A, Lopez E, Lieber D, Nikiforov A, et al.
Sci Rep . 2016 Apr; 6:24650. PMID: 27090146
Next generation sequencing is a transformative technology for discovering and diagnosing genetic disorders. However, high-throughput sequencing remains error-prone, necessitating variant confirmation in order to meet the exacting demands of clinical...
14.
Disease progression despite protective HLA expression in an HIV-infected transmission pair
Brener J, Gall A, Batorsky R, Riddell L, Buus S, Leitman E, et al.
Retrovirology . 2015 Jul; 12:55. PMID: 26123575
Background: The precise immune responses mediated by HLA class I molecules such as HLA-B*27:05 and HLA-B*57:01 that protect against HIV disease progression remain unclear. We studied a CRF01_AE clade HIV...
15.
The route of HIV escape from immune response targeting multiple sites is determined by the cost-benefit tradeoff of escape mutations
Batorsky R, Sergeev R, Rouzine I
PLoS Comput Biol . 2014 Oct; 10(10):e1003878. PMID: 25356981
Cytotoxic T lymphocytes (CTL) are a major factor in the control of HIV replication. CTL arise in acute infection, causing escape mutations to spread rapidly through the population of infected...
16.
HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck
Carlson J, Schaefer M, Monaco D, Batorsky R, Claiborne D, Prince J, et al.
Science . 2014 Jul; 345(6193):1254031. PMID: 25013080
Heterosexual transmission of HIV-1 typically results in one genetic variant establishing systemic infection. We compared, for 137 linked transmission pairs, the amino acid sequences encoded by non-envelope genes of viruses...
17.
Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection
Batorsky R, Kearney M, Palmer S, Maldarelli F, Rouzine I, Coffin J
Proc Natl Acad Sci U S A . 2011 Mar; 108(14):5661-6. PMID: 21436045
HIV adaptation to a host in chronic infection is simulated by means of a Monte-Carlo algorithm that includes the evolutionary factors of mutation, positive selection with varying strength among sites,...