Rebecca Batorsky
Overview
Explore the profile of Rebecca Batorsky including associated specialties, affiliations and a list of published articles.
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17
Citations
315
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Recent Articles
1.
Ali S, Perera G, Laird J, Batorsky R, Maron M, Rivas V, et al.
J Am Heart Assoc
. 2024 Dec;
14(1):e035780.
PMID: 39719426
Background: Hypertrophic cardiomyopathy (HCM) is a common heritable heart disease where the most frequently associated mutations occur in the myosin-binding protein C () sarcomere-associated gene. HCM is also a common...
2.
Jetton D, Muendlein H, Connolly W, Magri Z, Smirnova I, Batorsky R, et al.
Cell Rep
. 2024 Aug;
43(8):114641.
PMID: 39154339
Caspase-8-dependent pyroptosis has been shown to mediate host protection from Yersinia infection. For this mode of cell death, the kinase activity of receptor-interacting protein kinase 1 (RIPK1) is required, but...
3.
Batorsky R, Ceasrine A, Shook L, Kislal S, Bordt E, Devlin B, et al.
Cell Rep
. 2024 Jun;
43(6):114326.
PMID: 38848212
Maternal immune activation is associated with adverse offspring neurodevelopmental outcomes, many mediated by in utero microglial programming. As microglia remain inaccessible throughout development, identification of noninvasive biomarkers reflecting fetal brain...
4.
Bonaventura J, Rowin E, Chan R, Chin M, Puchnerova V, Polakova E, et al.
J Am Heart Assoc
. 2024 May;
13(10):e033565.
PMID: 38757491
Background: The genetic basis of hypertrophic cardiomyopathy (HCM) is complex, and the relationship between genotype status and clinical outcome is incompletely resolved. Methods And Results: We assessed a large international...
5.
Joshi V, Claiborne D, Pack M, Power K, Newman R, Batorsky R, et al.
J Virol
. 2024 Feb;
98(3):e0172023.
PMID: 38412036
The rational design of HIV-1 immunogens to trigger the development of broadly neutralizing antibodies (bNAbs) requires understanding the viral evolutionary pathways influencing this process. An acute HIV-1-infected individual exhibiting >50%...
6.
Batorsky R, Ceasrine A, Shook L, Kislal S, Bordt E, Devlin B, et al.
bioRxiv
. 2024 Jan;
PMID: 38187648
Maternal immune activation is associated with adverse offspring neurodevelopmental outcomes, many mediated by in utero microglial programming. As microglia remain inaccessible throughout development, identification of noninvasive biomarkers reflecting fetal brain...
7.
Laird J, Perera G, Batorsky R, Wang H, Arkun K, Chin M
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628806
Hypertrophic Cardiomyopathy (HCM) is a common inherited disorder that can lead to heart failure and sudden cardiac death, characterized at the histological level by focal areas of myocyte disarray, hypertrophy...
8.
Perera G, Power L, Larson A, Codden C, Awata J, Batorsky R, et al.
Int J Mol Sci
. 2023 Jul;
24(14).
PMID: 37511352
Barth Syndrome, a rare X-linked disorder affecting 1:300,000 live births, results from defects in Tafazzin, an acyltransferase that remodels cardiolipin and is essential for mitochondrial respiration. Barth Syndrome patients develop...
9.
Muendlein H, Connolly W, Cameron J, Jetton D, Magri Z, Smirnova I, et al.
Sci Immunol
. 2022 Dec;
7(78):eadd0665.
PMID: 36563168
TNF mediates a variety of biological processes including cellular proliferation, inflammatory responses, and cell death and is therefore associated with numerous pathologies including autoinflammatory diseases and septic shock. The inflammatory...
10.
Hanscom T, Woodward N, Batorsky R, Brown A, Roberts S, McVey M
Nucleic Acids Res
. 2022 Jul;
50(13):7465-7478.
PMID: 35819195
Alternative end joining (alt-EJ) mechanisms, such as polymerase theta-mediated end joining, are increasingly recognized as important contributors to inaccurate double-strand break repair. We previously proposed an alt-EJ model whereby short...