Raymond L Konger
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Explore the profile of Raymond L Konger including associated specialties, affiliations and a list of published articles.
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43
Citations
658
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Recent Articles
1.
Konger R, Xuei X, Derr-Yellin E, Fang F, Gao H, Liu Y
Cells
. 2024 Aug;
13(16).
PMID: 39195246
Given the importance of peroxisome proliferator-activated receptor (PPAR)-gamma in epidermal inflammation and carcinogenesis, we analyzed the transcriptomic changes observed in epidermal PPARγ-deficient mice (-/-). A gene set enrichment analysis revealed...
2.
Shugar A, Konger R, Rohan C, Travers J, Kim Y
Exp Dermatol
. 2024 Apr;
33(4):e15076.
PMID: 38610095
Nonmelanoma skin cancers remain the most widely diagnosed types of cancers globally. Thus, for optimal patient management, it has become imperative that we focus our efforts on the detection and...
3.
Konger R, Derr-Yellin E, Zimmers T, Katona T, Xuei X, Liu Y, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445339
Both agonist studies and loss-of-function models indicate that PPARγ plays an important role in cutaneous biology. Since PPARγ has a high level of basal activity, we hypothesized that epidermal PPARγ...
4.
Konger R, Ren L, Sahu R, Derr-Yellin E, Kim Y
Sci Rep
. 2020 Nov;
10(1):19200.
PMID: 33154396
With recurring carcinogen exposures, individual tumors develop in a field of genetic mutations through a stepwise process of clonal expansion and evolution. Once established, this "cancer field" persists in the...
5.
Thyagarajan A, Forino A, Konger R, Sahu R
Antioxidants (Basel)
. 2020 Jul;
9(8).
PMID: 32717779
Naturally occurring dietary agents present in a wide variety of plant products, are rich sources of phytochemicals possessing medicinal properties, and thus, have been used in folk medicine for ages...
6.
Konger R, Derr-Yellin E, Ermatov N, Ren L, Sahu R
Molecules
. 2019 Jun;
24(11).
PMID: 31212694
Recent evidence suggests that PPARγ agonists may promote anti-tumor immunity. We show that immunogenic PDV cutaneous squamous cell carcinoma (CSCC) tumors are rejected when injected intradermally at a low cell...
7.
Ren L, Konger R
Mol Carcinog
. 2019 May;
58(9):1589-1601.
PMID: 31111568
A variety of evidence suggests that peroxisome proliferator-activated receptor (PPAR)γ agonists may represent a potential pharmacologic target in the prevention or treatment of skin cancer. In particular, recent reports suggest...
8.
Konger R, Derr-Yellin E, Travers J, Ocana J, Sahu R
Oncotarget
. 2017 Dec;
8(58):98184-98199.
PMID: 29228682
It is known that ultraviolet B (UVB) induces PPARγ ligand formation while loss of murine epidermal PPARγ (-/-) promotes UVB-induced apoptosis, inflammation, and carcinogenesis. PPARγ is known to suppress tumor...
9.
Kim T, Visbal-Onufrak M, Konger R, Kim Y
Biomed Opt Express
. 2017 Dec;
8(11):5282-5296.
PMID: 29188120
Sensitive and accurate assessment of dermatologic inflammatory hyperemia in otherwise grossly normal-appearing skin conditions is beneficial to laypeople for monitoring their own skin health on a regular basis, to patients...
10.
Lakhter A, Hamilton J, Konger R, Brustovetsky N, Broxmeyer H, Naidu S
J Biol Chem
. 2016 Aug;
291(42):21869-21879.
PMID: 27539851
Tumors rely on multiple nutrients to meet cellular bioenergetics and macromolecular synthesis demands of rapidly dividing cells. Although the role of glucose and glutamine in cancer metabolism is well understood,...