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Ethel Derr-Yellin

Explore the profile of Ethel Derr-Yellin including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 199
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Recent Articles
1.
Konger R, Xuei X, Derr-Yellin E, Fang F, Gao H, Liu Y
Cells . 2024 Aug; 13(16). PMID: 39195246
Given the importance of peroxisome proliferator-activated receptor (PPAR)-gamma in epidermal inflammation and carcinogenesis, we analyzed the transcriptomic changes observed in epidermal PPARγ-deficient mice (-/-). A gene set enrichment analysis revealed...
2.
Konger R, Derr-Yellin E, Zimmers T, Katona T, Xuei X, Liu Y, et al.
Int J Mol Sci . 2021 Aug; 22(16). PMID: 34445339
Both agonist studies and loss-of-function models indicate that PPARγ plays an important role in cutaneous biology. Since PPARγ has a high level of basal activity, we hypothesized that epidermal PPARγ...
3.
Konger R, Ren L, Sahu R, Derr-Yellin E, Kim Y
Sci Rep . 2020 Nov; 10(1):19200. PMID: 33154396
With recurring carcinogen exposures, individual tumors develop in a field of genetic mutations through a stepwise process of clonal expansion and evolution. Once established, this "cancer field" persists in the...
4.
Konger R, Derr-Yellin E, Ermatov N, Ren L, Sahu R
Molecules . 2019 Jun; 24(11). PMID: 31212694
Recent evidence suggests that PPARγ agonists may promote anti-tumor immunity. We show that immunogenic PDV cutaneous squamous cell carcinoma (CSCC) tumors are rejected when injected intradermally at a low cell...
5.
Konger R, Derr-Yellin E, Travers J, Ocana J, Sahu R
Oncotarget . 2017 Dec; 8(58):98184-98199. PMID: 29228682
It is known that ultraviolet B (UVB) induces PPARγ ligand formation while loss of murine epidermal PPARγ (-/-) promotes UVB-induced apoptosis, inflammation, and carcinogenesis. PPARγ is known to suppress tumor...
6.
Konger R, Derr-Yellin E, Hojati D, Lutz C, Sundberg J
Exp Dermatol . 2016 Apr; 25(9):688-93. PMID: 27095432
Hairless albino Crl:SKH1-Hr(hr) mice are commonly utilized for studies in which hair or pigmentation would introduce an impediment to observational studies. Being an outbred strain, the SKH1 model suffers from...
7.
Blue E, DiGiuseppe R, Derr-Yellin E, Carlos Acosta J, Pay S, Hanenberg H, et al.
Pediatr Res . 2013 Nov; 75(2):266-72. PMID: 24232636
Background: Children born to mothers with gestational diabetes mellitus (GDM) experience increased risk of developing hypertension, type 2 diabetes mellitus, and obesity. Disrupted function of endothelial colony-forming cells (ECFCs) may...
8.
Liu Y, Ballman K, Li D, Khan S, Derr-Yellin E, Shou W, et al.
J Leukoc Biol . 2011 Nov; 91(2):333-40. PMID: 22106009
FA is a genetic disorder characterized by BM failure, developmental defects, and cancer predisposition. Previous studies suggest that FA patients exhibit alterations in immunologic function. However, it is unclear whether...
9.
Allen J, Jaffer Z, Park S, Burgin S, Hofmann C, Sells M, et al.
Blood . 2009 Jan; 113(12):2695-705. PMID: 19124833
Mast cells are key participants in allergic diseases via activation of high-affinity IgE receptors (FcepsilonRI) resulting in release of proinflammatory mediators. The biochemical pathways linking IgE activation to calcium influx...
10.
Ingram D, Lien I, Mead L, Estes M, Prater D, Derr-Yellin E, et al.
Diabetes . 2007 Dec; 57(3):724-31. PMID: 18086900
Objective: Emerging data demonstrate that maternal diabetes has long-term health consequences for offspring, including the development of hypertension. In adults, circulating endothelial progenitor cells (EPCs) participate in vascular repair, and...