Isis C Sroka
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Explore the profile of Isis C Sroka including associated specialties, affiliations and a list of published articles.
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11
Citations
204
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Recent Articles
1.
Das L, Anderson T, Gard J, Sroka I, Strautman S, Nagle R, et al.
J Cell Biochem
. 2016 Aug;
118(5):1038-1049.
PMID: 27509031
Laminin binding integrins α6 (CD49f) and α3 (CD49c) are persistently but differentially expressed in prostate cancer (PCa). Integrin internalization is an important determinant of their cell surface expression and function....
2.
Schwann Cells Increase Prostate and Pancreatic Tumor Cell Invasion Using Laminin Binding A6 Integrin
Sroka I, Chopra H, Das L, Gard J, Nagle R, Cress A
J Cell Biochem
. 2015 Aug;
117(2):491-9.
PMID: 26239765
Human pancreatic and prostate cancers metastasize along nerve axons during perineural invasion. The extracellular matrix laminin class of proteins is an abundant component of both myelinated and non-myelinated nerves. Analysis...
3.
Geffre C, Pond E, Pond G, Sroka I, Gard J, Skovan B, et al.
Am J Transl Res
. 2015 Apr;
7(2):348-55.
PMID: 25901201
Bone is a favored site for solid tumor metastasis, especially among patients with breast, lung or prostate carcinomas. Micro CT is a powerful and inexpensive tool that can be used...
4.
Kacsinta A, Rubenstein C, Sroka I, Pawar S, Gard J, Nagle R, et al.
Biochem Biophys Res Commun
. 2014 Dec;
454(2):335-40.
PMID: 25450398
Cancer metastasis is a multi-step process in which tumor cells gain the ability to invade beyond the primary tumor and colonize distant sites. The mechanisms regulating the metastatic process confer...
5.
Sroka I, Pond G, Nagle R, Porreca F, King T, Pestano G, et al.
Open Prost Cancer J
. 2011 Nov;
2:59-66.
PMID: 22081777
Existing clinical imaging procedures lack sensitivity and specificity in detecting early prostate cancer bone metastatic lesions. In this study, we developed a highly reproducible bone metastasis xenograft model and identified...
6.
Sroka I, Sandoval C, Chopra H, Gard J, Pawar S, Cress A
Mol Cancer Res
. 2011 Aug;
9(10):1319-28.
PMID: 21824975
The laminin-binding integrin α6β1 plays a major role in determining the aggressive phenotype of tumor cells during metastasis. Our previous work has shown that cleavage of the α6β1 integrin to...
7.
Sroka I, Anderson T, McDaniel K, Nagle R, Gretzer M, Cress A
J Cell Physiol
. 2010 May;
224(2):283-8.
PMID: 20432448
Metastasizing prostate tumor cells invade along nerves innervating the encapsulated human prostate gland in a process known as perineural invasion. The extracellular matrix laminin class of proteins line the neural...
8.
King T, Pawar S, Majuta L, Sroka I, Wynn D, Demetriou M, et al.
PLoS One
. 2008 Oct;
3(10):e3535.
PMID: 18958175
Of the estimated 565,650 people in the U.S. who will die of cancer in 2008, almost all will have metastasis. Breast, prostate, kidney, thyroid and lung cancers metastasize to the...
9.
Sroka I, Chen M, Cress A
Biochem Biophys Res Commun
. 2008 Aug;
375(3):410-3.
PMID: 18713621
Laminins are glycoproteins expressed in the basement membrane of multiple epithelial tissues. Previously described purification procedures for the human laminin variants laminin-5 (LN-332) and laminin-10 (LN-511) use tissue as starting...
10.
Sroka I, McDaniel K, Nagle R, Bowden G
Prostate
. 2008 Jan;
68(5):463-76.
PMID: 18196535
Background: MT1-MMP is a metalloproteinase involved in prostate cancer metastasis. The IGF-1R is a tyrosine kinase receptor involved with tumor progression and metastasis. The purpose of this investigation was to...