Rayhane Nchioua
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Explore the profile of Rayhane Nchioua including associated specialties, affiliations and a list of published articles.
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Citations
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Recent Articles
1.
Vlachou A, Nchioua R, Regensburger K, Kirchhoff F, Kmiec D
Sci Rep
. 2024 Sep;
14(1):20697.
PMID: 39237598
Human coronaviruses (hCoVs) infect millions of people every year. Among these, MERS, SARS-CoV-1, and SARS-CoV-2 caused significant morbidity and mortality and their emergence highlights the risk of possible future coronavirus...
2.
Volcic M, Nchioua R, Pastorio C, Zech F, Haussmann I, Sauter D, et al.
J Med Virol
. 2024 Jul;
96(7):e29783.
PMID: 38965890
Many COVID-19 patients suffer from gastrointestinal symptoms and impaired intestinal barrier function is thought to play a key role in Long COVID. Despite its importance, the impact of severe acute...
3.
Hagelauer E, Lotke R, Kmiec D, Hu D, Hohner M, Stopper S, et al.
Viruses
. 2023 Dec;
15(12).
PMID: 38140605
Coronavirus infection induces interferon-stimulated genes, one of which encodes Tetherin, a transmembrane protein inhibiting the release of various enveloped viruses from infected cells. Previous studies revealed that SARS-CoV encodes two...
4.
Pastorio C, Noettger S, Nchioua R, Zech F, Sparrer K, Kirchhoff F
iScience
. 2023 Nov;
26(11):108299.
PMID: 38026181
Additional mutations in the viral Spike protein helped the BA.2.12.1 and BA.4/5 SARS-CoV-2 Omicron subvariants to outcompete the parental BA.2 subvariant. Here, we determined the functional impact of mutations that...
5.
Viox E, Hoang T, Upadhyay A, Nchioua R, Hirschenberger M, Strongin Z, et al.
Sci Immunol
. 2023 Jul;
8(85):eadg0033.
PMID: 37506197
Type I interferons (IFN-I) are critical mediators of innate control of viral infections but also drive the recruitment of inflammatory cells to sites of infection, a key feature of severe...
6.
Nchioua R, Schundner A, Klute S, Koepke L, Hirschenberger M, Noettger S, et al.
Life Sci Alliance
. 2023 Mar;
6(6).
PMID: 36977594
The IFN system constitutes a powerful antiviral defense machinery. Consequently, effective IFN responses protect against severe COVID-19 and exogenous IFNs inhibit SARS-CoV-2 in vitro. However, emerging SARS-CoV-2 variants of concern...
7.
Xie Q, Prelli Bozzo C, Eiben L, Noettger S, Kmiec D, Nchioua R, et al.
iScience
. 2023 Mar;
26(4):106395.
PMID: 36968088
Opposing effects of interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) on SARS-CoV-2 infection have been reported. The reasons for this are unclear and the role of IFITMs in infection...
8.
Nchioua R, Diofano F, Noettger S, von Maltitz P, Stenger S, Zech F, et al.
Signal Transduct Target Ther
. 2022 Dec;
7(1):395.
PMID: 36566244
No abstract available.
9.
Hoang T, Viox E, Upadhyay A, Strongin Z, Tharp G, Pino M, et al.
bioRxiv
. 2022 Nov;
PMID: 36324810
Type-I interferons (IFN-I) are critical mediators of innate control of viral infections, but also drive recruitment of inflammatory cells to sites of infection, a key feature of severe COVID-19. Here,...
10.
Acharya D, Reis R, Volcic M, Liu G, Wang M, Chia B, et al.
Cell
. 2022 Sep;
185(19):3588-3602.e21.
PMID: 36113429
The current dogma of RNA-mediated innate immunity is that sensing of immunostimulatory RNA ligands is sufficient for the activation of intracellular sensors and induction of interferon (IFN) responses. Here, we...