Ravichandran Panchanathan
Overview
Explore the profile of Ravichandran Panchanathan including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
892
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0
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Recent Articles
1.
Bridges J, Safina C, Pirard B, Brown K, Filuta A, Panchanathan R, et al.
Elife
. 2022 Sep;
11.
PMID: 36073784
The mechanistic details of the tethered agonist mode of activation for the adhesion GPCR ADGRF5/GPR116 have not been completely deciphered. We set out to investigate the physiological importance of autocatalytic...
2.
Panchanathan R, Ramalingam V, Liu H, Choubey D
Life (Basel)
. 2021 Apr;
11(4).
PMID: 33923931
Increased levels of type I (T1) interferon (IFN)-inducible POP3 protein in myeloid cells inhibit activation of the AIM2 inflammasome and production of IL-1β and IL-18 proinflammatory cytokines. The mRNA levels...
3.
Jackson J, Hancock T, LaPrade E, Dogra P, Gann E, Masi T, et al.
mBio
. 2019 Jun;
10(3).
PMID: 31239384
Human cytomegalovirus (HCMV) is a betaherpesvirus that is a significant pathogen within newborn and immunocompromised populations. Morbidity associated with HCMV infection is the consequence of viral dissemination. HCMV has evolved...
4.
Choubey D, Panchanathan R
Cytokine
. 2019 Mar;
132:154682.
PMID: 30904426
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that exhibits a strong female bias (female-to-male ratio 9:1) in patients. Further, 40-60% SLE patients develop lupus nephritis (LN), which significantly...
5.
Choubey D, Panchanathan R
Clin Immunol
. 2017 Jan;
176:42-48.
PMID: 28062222
Type I interferons (IFN-α/β)-inducible PYRIN and HIN domain-containing protein family includes Absent in Melanoma 2 (murine Aim2 and human AIM2), murine p202, and human PYRIN-only protein 3 (POP3). The generation...
6.
Choubey D, Panchanathan R
Ageing Res Rev
. 2016 Apr;
28:27-36.
PMID: 27063514
DNA-damage induces a DNA-damage response (DDR) in mammalian cells. The response, depending upon the cell-type and the extent of DNA-damage, ultimately results in cell death or cellular senescence. DDR-induced signaling...
7.
Panchanathan R, Liu H, Choubey D
Oncotarget
. 2016 Apr;
7(19):28183-94.
PMID: 27058421
The molecular mechanisms by which hypoxia contributes to prostatic chronic inflammation (PCI) remain largely unknown. Because hypoxia stimulates the transcriptional activity of NF-κB, which "primes" cells for inflammasome activation by...
8.
Choubey D, Panchanathan R
J Immunol
. 2015 Nov;
195(10):4551-2.
PMID: 26546685
No abstract available.
9.
Panchanathan R, Liu H, Leung Y, Ho S, Choubey D
Mol Cell Endocrinol
. 2015 Aug;
415:45-55.
PMID: 26277401
Environmental factors contribute to the development of autoimmune diseases, including systemic lupus erythematosus (SLE), which exhibits a strong female bias (female-to-male ratio 9:1). However, the molecular mechanisms remain largely unknown....
10.
Panchanathan R, Liu H, Choubey D
Int J Toxicol
. 2015 Apr;
34(3):242-9.
PMID: 25878193
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates multiple cellular processes. The anticancer drug doxorubicin (DOX) can activate AhR-mediated transcription of target genes. Because DOX in cells...