Divaker Choubey
Overview
Explore the profile of Divaker Choubey including associated specialties, affiliations and a list of published articles.
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71
Citations
6907
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Recent Articles
1.
Choubey D
Ageing Res Rev
. 2022 Oct;
82:101765.
PMID: 36270606
Cellular changes that are linked to aging in humans include genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, cellular senescence, and altered intercellular communications. The extent of the changes in...
2.
Sawyer R, Hill E, Yokoyama J, Medvedovic M, Ren Y, Zhang X, et al.
Medicine (Baltimore)
. 2022 Jan;
101(3):e28645.
PMID: 35060553
The peripheral immune system has a key pathophysiologic role in Frontotemporal degeneration (FTD). We sought a comprehensive transcriptome-wide evaluation of gene expression alterations unique to the peripheral immune system in...
3.
Panchanathan R, Ramalingam V, Liu H, Choubey D
Life (Basel)
. 2021 Apr;
11(4).
PMID: 33923931
Increased levels of type I (T1) interferon (IFN)-inducible POP3 protein in myeloid cells inhibit activation of the AIM2 inflammasome and production of IL-1β and IL-18 proinflammatory cytokines. The mRNA levels...
4.
Choubey D
J Neuroinflammation
. 2019 Nov;
16(1):236.
PMID: 31771614
Cumulative evidence indicates that activation of innate immune responses in the central nervous system (CNS) induces the expression of type 1 interferons (T1 IFNs), a family of cytokines. The T1...
5.
Choubey D, Panchanathan R
Cytokine
. 2019 Mar;
132:154682.
PMID: 30904426
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that exhibits a strong female bias (female-to-male ratio 9:1) in patients. Further, 40-60% SLE patients develop lupus nephritis (LN), which significantly...
6.
Choubey D, Panchanathan R
Clin Immunol
. 2017 Jan;
176:42-48.
PMID: 28062222
Type I interferons (IFN-α/β)-inducible PYRIN and HIN domain-containing protein family includes Absent in Melanoma 2 (murine Aim2 and human AIM2), murine p202, and human PYRIN-only protein 3 (POP3). The generation...
7.
Choubey D
Cell Mol Life Sci
. 2016 Jun;
73(23):4383-4395.
PMID: 27328971
Recent studies utilizing chemical-induced colitis-associated and sporadic colon cancer in mouse models indicated a protective role for absent in melanoma 2 (Aim2) in colon epithelial cells. Accordingly, mutations in the...
8.
Hsieh H, Subramanian Vignesh K, Deepe Jr G, Choubey D, Shertzer H, Genter M
Toxicol In Vitro
. 2016 May;
35:24-30.
PMID: 27179668
Zinc is both an essential and potentially toxic metal. It is widely believed that oral zinc supplementation can reduce the effects of the common cold; however, there is strong clinical...
9.
Choubey D, Panchanathan R
Ageing Res Rev
. 2016 Apr;
28:27-36.
PMID: 27063514
DNA-damage induces a DNA-damage response (DDR) in mammalian cells. The response, depending upon the cell-type and the extent of DNA-damage, ultimately results in cell death or cellular senescence. DDR-induced signaling...
10.
Panchanathan R, Liu H, Choubey D
Oncotarget
. 2016 Apr;
7(19):28183-94.
PMID: 27058421
The molecular mechanisms by which hypoxia contributes to prostatic chronic inflammation (PCI) remain largely unknown. Because hypoxia stimulates the transcriptional activity of NF-κB, which "primes" cells for inflammasome activation by...