Ravi Kapur
Overview
Explore the profile of Ravi Kapur including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
4659
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0
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Recent Articles
1.
Edd J, Mishra A, Smith K, Kapur R, Maheswaran S, Haber D, et al.
iScience
. 2022 Jul;
25(8):104696.
PMID: 35880043
Circulating tumor cells (CTCs) enter the vasculature from solid tumors and disseminate widely to initiate metastases. Mining the metastatic-enriched molecular signatures of CTCs before, during, and after treatment holds unique...
2.
Sundaresan T, Dubash T, Zheng Z, Bardia A, Wittner B, Aceto N, et al.
Breast Cancer Res Treat
. 2021 Jun;
188(1):43-52.
PMID: 34101078
Purpose: Therapeutic efficacy of hormonal therapies to target estrogen receptor (ER)-positive breast cancer is limited by the acquisition of ligand-independent ESR1 mutations, which confer treatment resistance to aromatase inhibitors (AIs)....
3.
Mishra A, Dubash T, Edd J, Jewett M, Garre S, Karabacak N, et al.
Proc Natl Acad Sci U S A
. 2020 Jul;
117(29):16839-16847.
PMID: 32641515
Circulating tumor cell (CTC)-based liquid biopsies provide unique opportunities for cancer diagnostics, treatment selection, and response monitoring, but even with advanced microfluidic technologies for rare cell detection the very low...
4.
Edd J, Mishra A, Dubash T, Herrera S, Mohammad R, Williams E, et al.
Lab Chip
. 2020 Jan;
20(3):558-567.
PMID: 31934715
Circulating tumor cells (CTCs) are extremely rare in the blood, yet they account for metastasis. Notably, it was reported that CTC clusters (CTCCs) can be 50-100 times more metastatic than...
5.
Weng L, Lee G, Liu J, Kapur R, Toth T, Toner M
Lab Chip
. 2018 Nov;
18(24):3892-3902.
PMID: 30465050
Human infertility can be treated using assisted reproductive technology (ART) such as intracytoplasmic sperm injection (ICSI). But current ART techniques suffer from multiple cumbersome processes requiring technically skilled personnel. Microfluidics...
6.
Kwan T, Bardia A, Spring L, Giobbie-Hurder A, Kalinich M, Dubash T, et al.
Cancer Discov
. 2018 Aug;
8(10):1286-1299.
PMID: 30104333
The multiplicity of new therapies for breast cancer presents a challenge for treatment selection. We describe a 17-gene digital signature of breast circulating tumor cell (CTC)-derived transcripts enriched from blood,...
7.
Aceto N, Bardia A, Wittner B, Donaldson M, OKeefe R, Engstrom A, et al.
Mol Cancer Res
. 2018 Feb;
16(4):720-727.
PMID: 29453314
Molecular drivers underlying bone metastases in human cancer are not well understood, in part due to constraints in bone tissue sampling. Here, RNA sequencing was performed of circulating tumor cells...
8.
Hong X, Sullivan R, Kalinich M, Kwan T, Giobbie-Hurder A, Pan S, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(10):2467-2472.
PMID: 29453278
A subset of patients with metastatic melanoma have sustained remissions following treatment with immune checkpoint inhibitors. However, analyses of pretreatment tumor biopsies for markers predictive of response, including PD-1 ligand...
9.
Miyamoto D, Lee R, Kalinich M, LiCausi J, Zheng Y, Chen T, et al.
Cancer Discov
. 2018 Jan;
8(3):288-303.
PMID: 29301747
Blood-based biomarkers are critical in metastatic prostate cancer, where characteristic bone metastases are not readily sampled, and they may enable risk stratification in localized disease. We established a sensitive and...
10.
Fachin F, Spuhler P, Martel-Foley J, Edd J, Barber T, Walsh J, et al.
Sci Rep
. 2017 Sep;
7(1):10936.
PMID: 28883519
Circulating tumor cells (CTCs) are a treasure trove of information regarding the location, type and stage of cancer and are being pursued as both a diagnostic target and a means...