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Raul C Camacho

Explore the profile of Raul C Camacho including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 225
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Recent Articles
1.
Frikke-Schmidt H, Albarazanji K, Qi J, Frederick D, Steffen J, Kalyana-Sundaram S, et al.
J Pharmacol Exp Ther . 2025 Mar; 392(2):100002. PMID: 40023580
Acute kidney injury (AKI) is characterized by an abrupt decline in kidney function and has been associated with excess risks of death, kidney disease progression, and cardiovascular events. The kidney...
2.
Camacho R, Polidori D, Chen T, Chen B, Han Hsu H, Gao B, et al.
Diabetes Obes Metab . 2022 Dec; 25(4):1068-1079. PMID: 36546607
Aim: To develop an obese, insulin-resistant cynomolgus monkey model of non-alcoholic steatohepatitis (NASH) with fibrosis with a high fat/high cholesterol (HFHC) diet (with or without high fructose) and test its...
3.
Li W, Kirchner T, Ho G, Bonilla F, DAquino K, Littrell J, et al.
Diabetes Obes Metab . 2021 Jan; 22(12):2437-2450. PMID: 33463043
Aim: The aim of this study was to evaluate amino acids as glucagon receptor (GCGR)-specific biomarkers in rodents and cynomolgus monkeys in the presence of agonism of both glucagon-like peptide-1...
4.
Camacho R, You S, DAquino K, Li W, Wang Y, Gunnet J, et al.
MAbs . 2020 Aug; 12(1):1794687. PMID: 32744157
The long circulating half-life and inherently bivalent architecture of IgGs provide an ideal vehicle for presenting otherwise short-lived G-protein-coupled receptor agonists in a format that enables avidity-driven enhancement of potency....
5.
Moore M, Kelley D, Camacho R, Zafian P, Ye T, Lin S, et al.
Diabetes . 2018 Mar; 67(6):1173-1181. PMID: 29540491
We evaluated the hepatic and nonhepatic responses to glucose-responsive insulin (GRI). Eight dogs received GRI or regular human insulin (HI) in random order. A primed, continuous intravenous infusion of [3-H]glucose...
6.
Kang L, Camacho R, Li W, DAquino K, You S, Chuo V, et al.
Anal Chem . 2017 May; 89(11):6065-6075. PMID: 28457123
As therapeutic recombinant fusion proteins become more widely applicable for the treatment of various types of diseases, there is an increased demand for universal methods such as liquid chromatography (LC)-mass...
7.
Tozzo E, Bhat G, Cheon K, Camacho R
PLoS One . 2015 May; 10(5):e0126642. PMID: 25954816
Hyperinsulinemic-euglycemic clamps are considered the "gold standard" for assessing whole body insulin sensitivity. When used in combination with tracer dilution techniques and physiological insulin concentrations, insulin sensitization can be dissected...
8.
Camacho R, Zafian P, Achanfuo-Yeboah J, Manibusan A, Berger J
Eur J Pharmacol . 2013 Jul; 715(1-3):41-5. PMID: 23831019
Fibroblast growth factor 21 (FGF21) is a novel hormone-like polypeptide that when administered exogenously, has been shown to have beneficial effects on food intake, body weight, and metabolism. The in...
9.
Berglund E, Lee-Young R, Lustig D, Lynes S, Donahue E, Camacho R, et al.
J Clin Invest . 2009 Aug; 119(8):2412-22. PMID: 19662685
The hepatic energy state, defined by adenine nucleotide levels, couples metabolic pathways with energy requirements. This coupling is fundamental in the adaptive response to many conditions and is impaired in...
10.
Buettner C, Camacho R
Endocrinol Metab Clin North Am . 2008 Nov; 37(4):825-40. PMID: 19026934
The liver plays a pivotal role in the regulation of glucose metabolism because it is the key organ that maintains glucose levels during fasting. An emerging body of literature has...