Raquel Franco Leal
Overview
Explore the profile of Raquel Franco Leal including associated specialties, affiliations and a list of published articles.
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58
Citations
521
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Recent Articles
1.
Rodrigues B, Pascoal L, Genaro L, Warrak L, Rodrigues B, Coope A, et al.
Cells
. 2025 Feb;
14(4).
PMID: 39996742
Background: Crohn's disease (CD) is an inflammatory bowel disease marked by an abnormal immune response and excessive pro-inflammatory cytokines, leading to impaired protein processing and endoplasmic reticulum (ER) stress. This...
2.
Genaro L, Carron J, de Castro M, Franceschini A, Lourenco G, Cruz C, et al.
Int J Immunopathol Pharmacol
. 2025 Feb;
39:3946320251319379.
PMID: 39959979
Crohn's disease (CD) involves immune system interactions with intestinal tissue, driven by pro-inflammatory cytokines like Tumor Necrosis Factor (TNF-α). Adalimumab, targeting TNF-α, regulates associated inflammatory responses. Despite being humanized, it...
3.
Ceccato H, Silva T, Genaro L, Silva J, de Souza W, Oliveira P, et al.
Am J Transl Res
. 2025 Feb;
17(1):28-46.
PMID: 39959235
Introduction: Inflammatory Bowel Disease (IBD), encompassing Crohn's disease and ulcerative colitis, presents significant clinical challenges due to its heterogeneous nature and complex etiology. Recent advancements in biomedical research have enhanced...
4.
Gomes L, Genaro L, de Castro M, Ricci R, Pascoal L, Silva F, et al.
Therap Adv Gastroenterol
. 2024 Dec;
17:17562848241251949.
PMID: 39664232
Background: The treatment for Crohn's disease (CD) has increasingly required the use of biological agents. Safe and affordable tests have led to the active implementation of therapeutic drug monitoring (TDM)...
5.
Bonfitto P, Rodrigues B, Siqueira N, Genaro L, Rodrigues B, Oliveira P, et al.
Am J Cancer Res
. 2024 Dec;
14(11):5133-5153.
PMID: 39659922
Colorectal cancer (CRC) is one of the most widespread tumor types, and it stands as the second leading cause of disease-related mortality globally. Due to its adverse effects, which lead...
6.
Mazzaro M, de Paula A, Pascoal L, Genaro L, Pereira I, Rodrigues B, et al.
Pharmaceuticals (Basel)
. 2024 Nov;
17(11).
PMID: 39598430
Background/objectives: Crohn's disease (CD) is a chronic inflammatory disorder that significantly affects patients' quality of life; conventional treatments often provide limited relief. Methods: This systematic review and meta-analysis explored the...
7.
Chaim F, Pascoal L, de Castro M, Palma B, Rodrigues B, Fagundes J, et al.
Sci Rep
. 2024 Nov;
14(1):28698.
PMID: 39562789
Inflammatory bowel diseases (IBD) are idiopathic disorders characterized by chronic gastrointestinal inflammation. Given conventional therapies' adverse effects and clinical failures, novel approaches are being investigated. Recent studies have highlighted the...
8.
Silva J, de Souza W, Mello J, Ceccato H, Oliveira P, Ayrizono M, et al.
Am J Transl Res
. 2024 Nov;
16(10):6029-6040.
PMID: 39544780
Objective: To conduct a systematic review (SR) to find evidence for a connection between Crohn's disease (CD) and the gut-brain axis (GBA). Methods: This study conducted a systematic review (SR)...
9.
Moya A, Alexandrino T, Morari J, Reguengo L, Velloso L, Leal R, et al.
Foods
. 2024 Sep;
13(18).
PMID: 39335878
St. Hil. is considered a natural anti-inflammatory. In traditional medicine, it is used to reduce cholesterol levels in the treatment of obesity. Foods capable of conferring a protective and nutritious...
10.
Filho A, Pazin G, Genaro L, Oliveira P, Ayrizono M, Leal R
Int J Surg Case Rep
. 2024 Sep;
123:110271.
PMID: 39260341
Introduction: Hidradenitis Suppurativa (HS) is a chronic inflammatory disorder that affects the pilosebaceous unit. Squamous Cell Carcinoma (SCC) can emerge as a complication. Presentation Of Case: A 58-year-old male patient...