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Livia Bitencourt Pascoal

Explore the profile of Livia Bitencourt Pascoal including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 151
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Recent Articles
1.
Rodrigues B, Pascoal L, Genaro L, Warrak L, Rodrigues B, Coope A, et al.
Cells . 2025 Feb; 14(4). PMID: 39996742
Background: Crohn's disease (CD) is an inflammatory bowel disease marked by an abnormal immune response and excessive pro-inflammatory cytokines, leading to impaired protein processing and endoplasmic reticulum (ER) stress. This...
2.
Genaro L, Carron J, de Castro M, Franceschini A, Lourenco G, Cruz C, et al.
Int J Immunopathol Pharmacol . 2025 Feb; 39:3946320251319379. PMID: 39959979
Crohn's disease (CD) involves immune system interactions with intestinal tissue, driven by pro-inflammatory cytokines like Tumor Necrosis Factor (TNF-α). Adalimumab, targeting TNF-α, regulates associated inflammatory responses. Despite being humanized, it...
3.
Gomes L, Genaro L, de Castro M, Ricci R, Pascoal L, Silva F, et al.
Therap Adv Gastroenterol . 2024 Dec; 17:17562848241251949. PMID: 39664232
Background: The treatment for Crohn's disease (CD) has increasingly required the use of biological agents. Safe and affordable tests have led to the active implementation of therapeutic drug monitoring (TDM)...
4.
Mazzaro M, de Paula A, Pascoal L, Genaro L, Pereira I, Rodrigues B, et al.
Pharmaceuticals (Basel) . 2024 Nov; 17(11). PMID: 39598430
Background/objectives: Crohn's disease (CD) is a chronic inflammatory disorder that significantly affects patients' quality of life; conventional treatments often provide limited relief. Methods: This systematic review and meta-analysis explored the...
5.
Chaim F, Pascoal L, de Castro M, Palma B, Rodrigues B, Fagundes J, et al.
Sci Rep . 2024 Nov; 14(1):28698. PMID: 39562789
Inflammatory bowel diseases (IBD) are idiopathic disorders characterized by chronic gastrointestinal inflammation. Given conventional therapies' adverse effects and clinical failures, novel approaches are being investigated. Recent studies have highlighted the...
6.
Steigleder K, Pascoal L, Siqueira N, Simino L, Ayrizono M, Milanski Ferreira M, et al.
Gastro Hep Adv . 2024 Aug; 3(1):17-30. PMID: 39132178
Background And Aims: Recent evidence suggests that the mesenteric adipose tissue (MAT) near the affected intestine may play a role in Crohn's disease (CD) pathophysiology. Modulation of several transcripts has...
7.
Siqueira N, Pascoal L, Rodrigues B, de Castro M, Martins A, Araujo D, et al.
World J Clin Cases . 2023 May; 11(12):2740-2752. PMID: 37214580
Background: Although the gastrointestinal tract is the most affected by Crohn's disease (CD), the condition triggers other consequent manifestations, and iron deficiency anemia (IDA) is one of the most common....
8.
de Negreiros L, Pascoal L, Genaro L, Silva J, Rodrigues B, Camargo M, et al.
Am J Transl Res . 2022 Aug; 14(7):4406-4425. PMID: 35958439
Ulcerative colitis (UC) is a chronic intestinal inflammatory disease and familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease. Both diseases, despite being different, may require the same surgical...
9.
Rodrigues B, Dotti I, Pascoal L, Morari J, Esteller M, Coope A, et al.
Mediators Inflamm . 2022 Feb; 2022:6049500. PMID: 35185383
Ulcerative colitis (UC) is characterized by a chronic overproduction of proinflammatory cytokines. During an acute phase, the endoplasmic reticulum (ER) is overloaded and the protein folding process is impaired, a...
10.
Pascoal L, Palma B, Chaim F, de Castro M, Damazio T, Franceschini A, et al.
World J Exp Med . 2022 Jan; 12(1):1-15. PMID: 35096550
The resolution of inflammation is an active process, guided by specialized pro-resolution lipid mediators (SPMs). These mediators originate from polyunsaturated fatty acids, such as omega-3. Sufficient evidence suggests that the...