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Raphael Zidovetzki

Explore the profile of Raphael Zidovetzki including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 2012
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Recent Articles
1.
Bota D, Chung J, Dandekar M, Carrillo J, Kong X, Fu B, et al.
CNS Oncol . 2018 Aug; 7(3):CNS22. PMID: 30157683
Aim: ERC1671 is an allogeneic/autologous therapeutic glioblastoma (GBM) vaccine - composed of whole, inactivated tumor cells mixed with tumor cell lysates derived from the patient and three GBM donors. Methods:...
2.
Schijns V, Pretto C, Strik A, Gloudemans-Rijkers R, Deviller L, Pierre D, et al.
Int J Mol Sci . 2018 Aug; 19(9). PMID: 30150597
Glioblastoma is the most common form of brain cancer in adults that produces severe damage to the brain leading to a very poor survival prognosis. The standard of care for...
3.
Lancet D, Zidovetzki R, Markovitch O
J R Soc Interface . 2018 Jul; 15(144). PMID: 30045888
Life is that which replicates and evolves, but there is no consensus on how life emerged. We advocate a systems protobiology view, whereby the first replicators were assemblies of spontaneously...
4.
Armstrong D, Lancet D, Zidovetzki R
Astrobiology . 2018 Apr; 18(4):419-430. PMID: 29634319
We studied the simulated replication and growth of prebiotic vesicles composed of 140 phospholipids and cholesterol using our R-GARD (Real Graded Autocatalysis Replication Domain) formalism that utilizes currently extant lipids...
5.
Alarcon-Riquelme M, Ziegler J, Molineros J, Howard T, Moreno-Estrada A, Sanchez-Rodriguez E, et al.
Arthritis Rheumatol . 2015 Nov; 68(4):932-43. PMID: 26606652
Objective: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a strong genetic component. We undertook the present work to perform the first genome-wide association study on individuals from...
6.
Armstrong D, Eisenstein M, Zidovetzki R, Jacob C
J Biol Chem . 2015 Mar; 290(20):12595-602. PMID: 25795782
In a case-control association study with 3716 North Americans of Hispanic descent and 4867 North Americans of European descent, we show that the associations of rs17849502 (NCF2 His-389 → Gln)...
7.
Chung S, Brown E, Williams A, Ramos P, Berthier C, Bhangale T, et al.
J Am Soc Nephrol . 2014 Jun; 25(12):2859-70. PMID: 24925725
Lupus nephritis is a manifestation of SLE resulting from glomerular immune complex deposition and inflammation. Lupus nephritis demonstrates familial aggregation and accounts for significant morbidity and mortality. We completed a...
8.
Jacob C, Eisenstein M, Dinauer M, Ming W, Liu Q, John S, et al.
Proc Natl Acad Sci U S A . 2011 Dec; 109(2):E59-67. PMID: 22203994
Systemic lupus erythematosus (SLE), the prototypic systemic autoimmune disease, is a debilitating multisystem autoimmune disorder characterized by chronic inflammation and extensive immune dysregulation in multiple organ systems, resulting in significant...
9.
Ramos P, Criswell L, Moser K, Comeau M, Williams A, Pajewski N, et al.
PLoS Genet . 2011 Dec; 7(12):e1002406. PMID: 22174698
In spite of the well-known clustering of multiple autoimmune disorders in families, analyses of specific shared genes and polymorphisms between systemic lupus erythematosus (SLE) and other autoimmune diseases (ADs) have...
10.
Armstrong D, Markovitch O, Zidovetzki R, Lancet D
Phys Biol . 2011 Sep; 8(6):066001. PMID: 21946049
We present a new embodiment of the graded autocatalysis replication domain (GARD) for the growth, replication and evolution of lipid vesicles based on a semi-empirical foundation using experimentally measured kinetic...