Carl D Langefeld
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Explore the profile of Carl D Langefeld including associated specialties, affiliations and a list of published articles.
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497
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18754
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Recent Articles
1.
Behymer T, Sekar P, Demel S, Aziz Y, Coleman E, Williamson B, et al.
J Am Heart Assoc
. 2025 Mar;
:e024457.
PMID: 40055853
Background: Intracerebral hemorrhage (ICH) carries a 30-day mortality rate of 40% to 50% and a high burden of disability. Prior studies found that psychosocial stressors are associated with hypertension, ischemic...
2.
Ziai W, Woo D, Sansing L, Hanley D, Ostapkovich N, Triene K, et al.
BMJ Open
. 2025 Feb;
15(2):e094322.
PMID: 39915023
Background: The REpeated ASSEssment of SurvivorS (REASSESS) study will conduct long-term cognitive, functional and neuropsychiatric performance assessments to determine whether evacuation of spontaneous intracerebral haemorrhage (ICH) reduces the risk of...
3.
Camalan S, Langefeld C, Zinnia A, McKee B, Carlson M, Deep N, et al.
Otolaryngol Head Neck Surg
. 2024 Sep;
172(1):152-161.
PMID: 39221462
Objective: This study investigated the comparative performance of ear, nose, and throat (ENT) physicians in correctly detecting ear abnormalities when reviewing digital otoscopy imaging using 3 different visualization methods, including...
4.
Wang Q, Kim T, Martinez-Bonet M, Aguiar V, Sim S, Cui J, et al.
Nat Commun
. 2024 Aug;
15(1):6804.
PMID: 39122710
Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We...
5.
Das S, Comeau M, Langefeld C
Metabolomics
. 2024 Aug;
20(5):91.
PMID: 39096438
Introduction: Variation in DNA methylation (DNAm) in adipose tissue is associated with the pathogenesis of obesity and insulin resistance. The activity of enzymes involved in altering DNAm levels is dependent...
6.
Lincoln M, Connally N, Axisa P, Gasperi C, Mitrovic M, van Heel D, et al.
Nat Genet
. 2024 May;
56(5):838-845.
PMID: 38741015
Autoimmune and inflammatory diseases are polygenic disorders of the immune system. Many genomic loci harbor risk alleles for several diseases, but the limited resolution of genetic mapping prevents determining whether...
7.
Wang Q, Martinez-Bonet M, Kim T, Sparks J, Ishigaki K, Chen X, et al.
Cell Genom
. 2024 Feb;
4(2):100502.
PMID: 38359789
No abstract available.
8.
Venema W, Hiddingh S, van Loosdregt J, Bowes J, Balliu B, de Boer J, et al.
Cell Genom
. 2024 Jan;
4(1):100460.
PMID: 38190099
Single-nucleotide polymorphisms (SNPs) near the ERAP2 gene are associated with various autoimmune conditions, as well as protection against lethal infections. Due to high linkage disequilibrium, numerous trait-associated SNPs are correlated...
9.
A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness
Langsten K, Shi L, Wilson A, Lumia S, Westwood B, Skeen A, et al.
Cancers (Basel)
. 2023 Dec;
15(24).
PMID: 38136319
Most women diagnosed with breast cancer (BC) have estrogen receptor alpha-positive (ER+) disease. The current mouse models of ER+ BC often rely on exogenous estrogen to encourage metastasis, which modifies...
10.
de las Fuentes L, Schwander K, Brown M, Bentley A, Winkler T, Sung Y, et al.
Front Genet
. 2023 Nov;
14:1235337.
PMID: 38028628
Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density...