Raphael Wiedey
Overview
Explore the profile of Raphael Wiedey including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
48
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0
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Recent Articles
1.
Kokott M, Breitkreutz J, Wiedey R
Int J Pharm X
. 2024 Apr;
7:100243.
PMID: 38585343
In recent years, the application of fixed dose combinations of antiretroviral drugs in HIV therapy has been established. Despite numerous therapeutic benefits, this approach poses several challenges for the formulation...
2.
Flugel K, Wiedey R, Riehl C, Kaminski I, Riehl M
Int J Pharm
. 2024 Mar;
655:124008.
PMID: 38493837
Film-coated tablets as solid oral dosage forms are a well-accepted way of administering drugs but are not without specific challenges during manufacturing. One relevant criterion of the final product is...
3.
Kokott M, Klinken S, Breitkreutz J, Wiedey R
Int J Pharm
. 2022 Dec;
631:122493.
PMID: 36528189
The formulation development of amorphous solid dispersions (ASDs) towards a patient-friendly oral solid dosage form is proving to be still challenging. To increase patient's compliance orodispersible tablets (ODTs) can be...
4.
Blundell R, Butterworth P, Charlier A, Daurio D, Degenhardt M, Harris D, et al.
J Pharm Sci
. 2022 Aug;
111(11):2943-2954.
PMID: 35973604
Titanium dioxide (in the form of E171) is a ubiquitous excipient in tablets and capsules for oral use. In the coating of a tablet or in the shell of a...
5.
Rahman-Yildir J, Wiedey R, Breitkreutz J
Int J Pharm
. 2022 Jul;
624:121984.
PMID: 35803532
Urinary tract disorders come at great discomfort to the patients suffering from them. To treat them, several potent drug substances are available but unfortunately, systemic drug therapy often comes along...
6.
Wiedey R, Kokott M, Breitkreutz J
Expert Opin Drug Deliv
. 2021 Nov;
18(12):1873-1890.
PMID: 34822316
Introduction: Child appropriate dosage forms are indispensable in modern medicine and are a prerequisite for successful pediatric drug therapy. For years, experts have called for a paradigm shift, from liquid...
7.
Muller M, Wiedey R, Hoheisel W, Serno P, Breitkreutz J
Eur J Pharm Biopharm
. 2021 Nov;
169:189-199.
PMID: 34756974
Poor solubility of drug candidates is a well-known and thoroughly studied challenge in the development of oral dosage forms. One important approach to tackle this challenge is the formulation as...
8.
Kokott M, Lura A, Breitkreutz J, Wiedey R
Eur J Pharm Biopharm
. 2021 Sep;
168:122-130.
PMID: 34474110
Pediatric, geriatric, and other patients who suffer from swallowing difficulties represent a special patient group, where an increased need in appropriate formulation development is required. To overcome these mostly swallowability...
9.
Radtke J, Wiedey R, Kleinebudde P
Pharm Dev Technol
. 2021 Aug;
26(9):989-999.
PMID: 34387137
Titanium dioxide (TiO) is one of the most commonly used pharmaceutical excipients. It is widely used as a white pigment in tablet and pellet coatings. However, it has recently been...
10.
Ponsar H, Wiedey R, Quodbach J
Pharmaceutics
. 2020 Jun;
12(6).
PMID: 32503216
Fused deposition modeling (FDM) is a 3D-printing technology of rising interest for the manufacturing of customizable solid dosage forms. The coupling of hot-melt extrusion with FDM is favored to allow...