Jorg Breitkreutz
Overview
Explore the profile of Jorg Breitkreutz including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
1349
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Recent Articles
1.
Lura V, Lura A, Breitkreutz J, Klingmann V
Eur J Pharm Biopharm
. 2025 Feb;
:114655.
PMID: 39922507
Mini-tablets have recently raised huge interest in pharmaceutical industry. The present review aims to identify the rational, the opportunities and challenges of this emerging small solid drug dosage form by...
2.
Lammerding L, Arora A, Braun S, Breitkreutz J
Int J Pharm
. 2024 Dec;
670:125102.
PMID: 39708846
Transdermal drug delivery using microneedle array patches has been investigated using a wide range of drug substances. Inkjet printing and micromolding are established methods for the production of microneedle array...
3.
Holken J, Wurz A, Friedrich K, Bottcher P, Asskali D, Stark H, et al.
Sci Rep
. 2024 Dec;
14(1):30158.
PMID: 39627401
In the past decades studies investigating the dendritic cell (DC) activation have been conducted almost exclusively in animal models. However, due to species-specific differences in the DC subsets, there is...
4.
Thissen J, Klassen M, Hacker M, Breitkreutz J, Teutenberg T, Fischer B
Anal Bioanal Chem
. 2024 Nov;
417(2):335-344.
PMID: 39556139
The analysis of serum for biomarkers is a standard method in clinical diagnosis and health assessment. The application of Raman spectroscopy to probe biomarkers in serum is increasingly investigated due...
5.
Bottcher P, Steinmeyer L, Stark H, Breitkreutz J, Mewes K
Toxicol In Vitro
. 2024 Sep;
102:105948.
PMID: 39343070
The MUTZ-3 cell line is a surrogate for Langerhans cells (LCs) employed in New Approach Methodologies for assessing the skin sensitizing potential of chemicals. However, MUTZ-3 cells must first be...
6.
Siegmund P, Klinken S, Hacker M, Breitkreutz J, Fischer B
Talanta
. 2024 Jun;
277:126353.
PMID: 38838561
In this study, deep UV resonance Raman spectroscopy (DUV-RRS) was coupled with high performance liquid chromatography (HPLC) to be applied in the field of pharmaceutical analysis. Naproxen, Metformin and Epirubicin...
7.
Page S, Rode T, Breitkreutz J, Wagner-Hattler L
Eur J Pharm Biopharm
. 2024 Apr;
199:114294.
PMID: 38636884
Recently, APV organized in collaboration with Fette Compacting GmbH a course on current use and future opportunities of minitablets. The course including a workshop was attended by 30 participants and...
8.
Kokott M, Breitkreutz J, Wiedey R
Int J Pharm X
. 2024 Apr;
7:100243.
PMID: 38585343
In recent years, the application of fixed dose combinations of antiretroviral drugs in HIV therapy has been established. Despite numerous therapeutic benefits, this approach poses several challenges for the formulation...
9.
Lura V, Klinken S, Breitkreutz J
Eur J Pharm Biopharm
. 2024 Feb;
198:114236.
PMID: 38423137
External lubrication is an alternative to internal lubrication and its related detrimental effects on properties of tablets like tensile strength (TS). However, to date there are hardly any systematic investigations...
10.
Chamberlain R, Breitkreutz J, Fischer B
Pharm Dev Technol
. 2024 Feb;
29(3):258-264.
PMID: 38407128
The aim of this study was to evaluate the suitability of a non-disruptive Raman spectroscopic method to quantify drug concentrations below 5 w% within a polymer matrix produced by hot-melt...