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Raphael Ferreira

Explore the profile of Raphael Ferreira including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 843
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Recent Articles
1.
Koeppel J, Ferreira R, Vanderstichele T, Riedmayr L, Peets E, Girling G, et al.
Science . 2025 Jan; 387(6733):eado3979. PMID: 39883775
We lack tools to edit DNA sequences at scales necessary to study 99% of the human genome that is noncoding. To address this gap, we applied CRISPR prime editing to...
2.
Abbott K, Subudhi S, Ferreira R, Gultekin Y, Steinbuch S, Munim M, et al.
bioRxiv . 2024 Nov; PMID: 39484531
Cancer metastasis is a major contributor to patient morbidity and mortality, yet the factors that determine the organs where cancers can metastasize are incompletely understood. In this study, we quantify...
3.
Do B, Hsu P, Vermeulen S, Wang Z, Hirz T, Abbott K, et al.
Dev Cell . 2024 Jun; 59(16):2203-2221.e15. PMID: 38823395
Control of cellular identity requires coordination of developmental programs with environmental factors such as nutrient availability, suggesting that perturbing metabolism can alter cell state. Here, we find that nucleotide depletion...
4.
Riedmayr L, Hinrichsmeyer K, Thalhammer S, Mittas D, Karguth N, Otify D, et al.
Nat Commun . 2023 Oct; 14(1):6578. PMID: 37852949
Large genes including several CRISPR-Cas modules like gene activators (CRISPRa) require dual adeno-associated viral (AAV) vectors for an efficient in vivo delivery and expression. Current dual AAV vector approaches have...
5.
Abbott K, Ali A, Casalena D, Do B, Ferreira R, Cheah J, et al.
Cell Chem Biol . 2023 Sep; 30(9):1156-1168.e7. PMID: 37689063
A challenge for screening new anticancer drugs is that efficacy in cell culture models is not always predictive of efficacy in patients. One limitation of standard cell culture is a...
6.
Neto E, Dadkhah S, Ferreira R, Zohourian A, Lu R, Ghorbani A
Sensors (Basel) . 2023 Jul; 23(13). PMID: 37447792
Nowadays, the Internet of Things (IoT) concept plays a pivotal role in society and brings new capabilities to different industries. The number of IoT solutions in areas such as transportation...
7.
Sandoval L, Cafundo N, Ferreira R, Segovia S, Rosa X
Clin Case Rep . 2023 Jun; 11(6):e7485. PMID: 37305874
The Rumpel-Leede sign, characterized by a non-blanching petechial rash distal to venous occlusion, has historically been associated with thrombocytopenia and capillary fragility. This phenomenon has been observed in various situations...
8.
Abbott K, Ali A, Casalena D, Do B, Ferreira R, Cheah J, et al.
bioRxiv . 2023 Mar; PMID: 36909640
A challenge for screening new candidate drugs to treat cancer is that efficacy in cell culture models is not always predictive of efficacy in patients. One limitation of standard cell...
9.
Skrekas C, Ferreira R, David F
Methods Mol Biol . 2022 Jul; 2513:39-57. PMID: 35781199
Metabolic engineering of microbial cells is the discipline of optimizing microbial metabolism to enable and improve the production of target molecules ranging from biofuels and chemical building blocks to high-value...
10.
Ferraro G, Ali A, Luengo A, Kodack D, Deik A, Abbott K, et al.
Nat Cancer . 2022 Feb; 2(11):1243. PMID: 35122065
No abstract available.