Randy L Johnson
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Explore the profile of Randy L Johnson including associated specialties, affiliations and a list of published articles.
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112
Citations
7841
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Recent Articles
1.
SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling
Su D, Li Y, Zhang W, Gao H, Cheng Y, Hou Y, et al.
J Clin Invest
. 2023 Oct;
133(20).
PMID: 37843276
The loss of contact inhibition is a key step during carcinogenesis. The Hippo-Yes-associated protein (Hippo/YAP) pathway is an important regulator of cell growth in a cell density-dependent manner. However, how...
2.
Kern J, Tilston-Lunel A, Federico A, Ning B, Mueller A, Peppler G, et al.
Nat Commun
. 2022 Nov;
13(1):7198.
PMID: 36443313
Basal-like breast cancers, an aggressive breast cancer subtype that has poor treatment options, are thought to arise from luminal mammary epithelial cells that undergo basal plasticity through poorly understood mechanisms....
3.
Wang C, Feng X, Su D, Chen Z, Wang S, Tang M, et al.
Proc Natl Acad Sci U S A
. 2022 Jun;
119(25):e2121779119.
PMID: 35704761
Cell surface proteins play essential roles in various biological processes and are highly related to cancer development. They also serve as important markers for cell identity and targets for pharmacological...
4.
Lee S, Yim S, Jeong Y, Li Q, Kang S, Sohn B, et al.
Hepatology
. 2022 Mar;
76(6):1634-1648.
PMID: 35349735
Background And Aims: Although many studies revealed transcriptomic subtypes of HCC, concordance of the subtypes are not fully examined. We aim to examine a consensus of transcriptomic subtypes and correlate...
5.
Weigel W, Williams B, Hanson N, Blackmore C, Johnson R, Nissen G, et al.
Anesthesiology
. 2022 Feb;
136(6):901-915.
PMID: 35188958
Background: Residual neuromuscular blockade can be avoided with quantitative neuromuscular monitoring. The authors embarked on a professional practice initiative to attain documented train-of-four ratios greater than or equal to 0.90...
6.
Liu Q, Li J, Zhang W, Xiao C, Zhang S, Nian C, et al.
Cell
. 2021 Oct;
184(22):5559-5576.e19.
PMID: 34678143
Glucose consumption is generally increased in tumor cells to support tumor growth. Interestingly, we report that glycogen accumulation is a key initiating oncogenic event during liver malignant transformation. We found...
7.
Contreras X, Amberg N, Davaatseren A, Hansen A, Sonntag J, Andersen L, et al.
Cell Rep
. 2021 Jun;
35(12):109274.
PMID: 34161767
Mosaic analysis with double markers (MADM) offers one approach to visualize and concomitantly manipulate genetically defined cells in mice with single-cell resolution. MADM applications include the analysis of lineage, single-cell...
8.
Tamura T, Kodama T, Sato K, Murai K, Yoshioka T, Shigekawa M, et al.
J Clin Invest
. 2021 May;
131(13).
PMID: 34032634
The role of PI3K and Hippo signaling in chronic pancreatitis (CP) pathogenesis is unclear. Therefore, we assessed the involvement of these pathways in CP by examining the PI3K and Hippo...
9.
Dong X, Song S, Li Y, Fan Y, Wang L, Wang R, et al.
Gut
. 2021 Mar;
71(3):467-478.
PMID: 33785559
Background: Gastric adenocarcinoma (GAC) is a lethal disease with limited therapeutic options. Genetic alterations in chromatin remodelling gene AT-rich interactive domain 1A () and mTOR pathway activation occur frequently in...
10.
Ma S, Wu Z, Yang F, Zhang J, Johnson R, Rosenfeld M, et al.
Nature
. 2021 Mar;
591(7848):E1-E10.
PMID: 33658690
No abstract available.