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Randy F Crossland

Explore the profile of Randy F Crossland including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 167
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Recent Articles
1.
Crossland R, Balasa A, Ramakrishnan R, Mahadevan S, Fiorotto M, Van den Veyver I
PLoS One . 2018 Jul; 13(7):e0201079. PMID: 30016362
[This corrects the article DOI: 10.1371/journal.pone.0170127.].
2.
Crossland R, Balasa A, Ramakrishnan R, Mahadevan S, Fiorotto M, Van den Veyver I
PLoS One . 2017 Jan; 12(1):e0170127. PMID: 28099477
Offspring of murine dams chronically fed a protein-restricted diet have an increased risk for metabolic and neurobehavioral disorders. Previously we showed that adult offspring, developmentally exposed to a chronic maternal...
3.
Durgan D, Crossland R, Bryan Jr R
J Cereb Blood Flow Metab . 2016 Nov; 37(8):2806-2819. PMID: 27798273
Circadian clock components oscillate in cells of the cardiovascular system. Disruption of these oscillations has been observed in cardiovascular diseases. We hypothesized that obstructive sleep apnea, which is associated with...
4.
Burdette A, Paredes R, Crossland R, Macko A, Aden J, Sheppard F
Shock . 2016 May; 46(3 Suppl 1):115-22. PMID: 27172162
Background: Uncontrolled hemorrhage (UH), the leading cause of potentially survivable combat-related death, elicits a deleterious inflammatory response. Our group previously reported an increased secretion of pro-inflammatory cytokines in a novel...
5.
Crossland R, Mitchell A, Macko A, Aden J, Campbell J, Sheppard F
J Trauma Acute Care Surg . 2016 Jan; 80(4):610-6. PMID: 26808041
Background: Heart rate (HR), systolic blood pressure (SBP) and mean arterial pressure (MAP) are traditionally used to guide patient triage and resuscitation; however, they correlate poorly to shock severity. Therefore,...
6.
Macko A, Crossland R, Cap A, Fryer D, Mitchell T, Pusateri A, et al.
J Trauma Acute Care Surg . 2016 Jan; 80(4):617-24. PMID: 26808038
Background: Hemorrhage remains the leading cause of potentially survivable trauma mortality. Recent reports indicate that injuries sustained in noncompressible anatomic locations (i.e., truncal and junctional) account for 86.5% of hemorrhage-related...
7.
Sheppard F, Macko A, Fryer D, Ozuna K, Brown A, Crossland R, et al.
Shock . 2015 Feb; 44 Suppl 1:114-22. PMID: 25692254
Hemorrhage is the leading cause of potentially survivable trauma mortality, necessitating the development of improved therapeutic interventions. The objective of this study was to develop and characterize a reproducible clinically...
8.
Durgan D, Crossland R, Lloyd E, Phillips S, Bryan R
J Cereb Blood Flow Metab . 2014 Nov; 35(3):402-11. PMID: 25425077
Obstructive sleep apnea (OSA) is associated with cerebrovascular diseases. However, little is known regarding the effects of OSA on the cerebrovascular wall. We tested the hypothesis that OSA augments endothelin-1...
9.
Crossland R, Durgan D, Lloyd E, Phillips S, Reddy A, Marrelli S, et al.
Am J Physiol Regul Integr Comp Physiol . 2013 Jun; 305(4):R334-42. PMID: 23761641
Obstructive sleep apnea (OSA), a condition in which the upper airway collapses during sleep, is strongly associated with metabolic and cardiovascular diseases. Little is known how OSA affects the cerebral...
10.
Lloyd E, Pandit L, Crossland R, Marrelli S, Bryan Jr R
Am J Physiol Regul Integr Comp Physiol . 2013 May; 305(1):R60-7. PMID: 23637138
K2P6.1 or TWIK-2, a two-pore domain K channel, is an important regulator of cardiovascular function. K2P6.1 is highly expressed in vascular smooth muscle and endothelium. Mice (8-12 wk) lacking functional...