David J Durgan
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Explore the profile of David J Durgan including associated specialties, affiliations and a list of published articles.
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36
Citations
2221
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Recent Articles
1.
Durgan D, Zubcevic J, Vijay-Kumar M, Yang T, Manandhar I, Aryal S, et al.
Hypertension
. 2024 Apr;
81(5):951-963.
PMID: 38630799
No abstract available.
2.
Aryal S, Manandhar I, Mei X, Yeoh B, Tummala R, Saha P, et al.
Camb Prism Precis Med
. 2024 Mar;
1:e26.
PMID: 38550938
The single largest contributor to human mortality is cardiovascular disease, the top risk factor for which is hypertension (HTN). The last two decades have placed much emphasis on the identification...
3.
Ayyaswamy S, Shi H, Zhang B, Bryan Jr R, Durgan D
J Am Heart Assoc
. 2023 Jun;
12(11):e029218.
PMID: 37260032
Background Obstructive sleep apnea (OSA) is an independent risk factor for the development of hypertension. We have demonstrated that OSA induces gut dysbiosis, and this dysbiotic microbiota contributes to hypertension....
4.
5.
Shi H, Nelson J, Phillips S, Petrosino J, Bryan R, Durgan D
Sci Rep
. 2022 May;
12(1):8534.
PMID: 35595870
Gut dysbiosis, a pathological imbalance of bacteria, has been shown to contribute to the development of hypertension (HT), systemic- and neuro-inflammation, and blood-brain barrier (BBB) disruption in spontaneously hypertensive stroke...
6.
Li N, Durgan D, Wehrens X
Cardiovasc Res
. 2021 Dec;
118(3):657-659.
PMID: 34849621
No abstract available.
7.
Shi H, Zhang B, Abo-Hamzy T, Nelson J, Ambati C, Petrosino J, et al.
Circ Res
. 2021 Feb;
128(9):1240-1254.
PMID: 33596669
[Figure: see text].
8.
Nelson J, Phillips S, Ganesh B, Petrosino J, Durgan D, Bryan R
FASEB J
. 2021 Jan;
35(2):e21201.
PMID: 33496989
In recent years, it has become apparent that the gut microbiome can influence the functioning and pathological states of organs and systems throughout the body. In this study, we tested...
9.
Lee J, Venna V, Durgan D, Shi H, Hudobenko J, Putluri N, et al.
Gut Microbes
. 2020 Sep;
12(1):1-14.
PMID: 32897773
Aging is associated with cognitive decline and decreased concentrations of short-chain fatty acids (SCFAs) in the gut. SCFAs are significant in that they are protective to the gut and other...
10.
Lee J, dAigle J, Atadja L, Quaicoe V, Honarpisheh P, Ganesh B, et al.
Circ Res
. 2020 May;
127(4):453-465.
PMID: 32354259
Rationale: The elderly experience profound systemic responses after stroke, which contribute to higher mortality and more severe long-term disability. Recent studies have revealed that stroke outcomes can be influenced by...