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Ran Kafri

Explore the profile of Ran Kafri including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 2015
Followers 0
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Recent Articles
1.
Liu S, Tan C, Melo-Gavin C, Ginzberg M, Blutrich R, Patel N, et al.
Elife . 2025 Jan; 14. PMID: 39791360
Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell size checkpoints,...
2.
Liu S, Tan C, Tyers M, Zetterberg A, Kafri R
Front Cell Dev Biol . 2022 Nov; 10:949382. PMID: 36393871
The human body is programmed with definite quantities, magnitudes, and proportions. At the microscopic level, such definite sizes manifest in individual cells - different cell types are characterized by distinct...
3.
Rohban M, Fuller A, Tan C, Goldstein J, Syangtan D, Gutnick A, et al.
Cell Syst . 2022 Sep; 13(9):724-736.e9. PMID: 36057257
Identifying the chemical regulators of biological pathways is a time-consuming bottleneck in developing therapeutics and research compounds. Typically, thousands to millions of candidate small molecules are tested in target-based biochemical...
4.
Badr H, Blutrich R, Chan K, Tong J, Taylor P, Zhang W, et al.
J Mol Biol . 2022 May; 434(13):167636. PMID: 35595168
Proteome analysis revealed signatures of co-expressed upregulated metabolism proteins highly conserved between primary and non-small cell lung cancer (NSCLC) patient-derived xenograft tumors (Li et al. 2014, Nat. Communications 5:5469). The...
5.
Kaufman T, Nitzan E, Firestein N, Ginzberg M, Iyengar S, Patel N, et al.
Nat Commun . 2022 May; 13(1):2725. PMID: 35585055
While multiplexing samples using DNA barcoding revolutionized the pace of biomedical discovery, multiplexing of live imaging-based applications has been limited by the number of fluorescent proteins that can be deconvoluted...
6.
Scepanovic G, Hunter M, Kafri R, Fernandez-Gonzalez R
Cell Rep . 2021 Oct; 37(3):109874. PMID: 34686334
Embryos repair wounds rapidly, with no inflammation or scarring, in a process that involves polarization of the actomyosin cytoskeleton. Actomyosin polarization results in the assembly of a contractile cable around...
7.
Tan C, Ginzberg M, Webster R, Iyengar S, Liu S, Papadopoli D, et al.
Dev Cell . 2021 May; 56(12):1756-1769.e7. PMID: 34022133
While molecules that promote the growth of animal cells have been identified, it remains unclear how such signals are orchestrated to determine a characteristic target size for different cell types....
8.
Francisco M, Wanggou S, Fan J, Dong W, Chen X, Momin A, et al.
J Exp Med . 2020 Feb; 217(5). PMID: 32097463
Ion channels represent a large class of drug targets, but their role in brain cancer is underexplored. Here, we identify that chloride intracellular channel 1 (CLIC1) is overexpressed in human...
9.
Demian W, Persaud A, Jiang C, Coyaud E, Liu S, Kapus A, et al.
Cell Rep . 2019 May; 27(6):1886-1896.e6. PMID: 31067471
mTORC1 regulates cellular growth and is activated by growth factors and by essential amino acids such as Leu. Leu enters cells via the Leu transporter LAT1-4F2hc (LAT1). Here we show...
10.
Anzi S, Stolovich-Rain M, Klochendler A, Fridlich O, Helman A, Paz-Sonnenfeld A, et al.
Dev Cell . 2018 Jun; 45(6):726-737.e3. PMID: 29920277
Developmental processes in different mammals are thought to share fundamental cellular mechanisms. We report a dramatic increase in cell size during postnatal pancreas development in rodents, accounting for much of...