Ramya Nandakumar
Overview
Explore the profile of Ramya Nandakumar including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
550
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0
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Recent Articles
1.
Prabakaran T, Troldborg A, Kumpunya S, Alee I, Marinkovic E, Windross S, et al.
EBioMedicine
. 2021 Apr;
66:103314.
PMID: 33813142
Background: Nucleic acids are potent stimulators of type I interferon (IFN-I) and antiviral defense, but may also promote pathological inflammation. A range of diseases are characterized by elevated IFN-I, including...
2.
Zhang B, Nandakumar R, Reinert L, Huang J, Laustsen A, Gao Z, et al.
Nat Immunol
. 2020 Sep;
21(11):1468-1469.
PMID: 32929276
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
3.
Zhang B, Nandakumar R, Reinert L, Huang J, Laustsen A, Gao Z, et al.
Nat Immunol
. 2020 Jul;
21(8):868-879.
PMID: 32690950
STING is essential for control of infections and for tumor immunosurveillance, but it can also drive pathological inflammation. STING resides on the endoplasmic reticulum (ER) and traffics following stimulation to...
4.
Nandakumar R, Paludan S
J Biol Chem
. 2019 Nov;
294(45):16509-16510.
PMID: 31704772
is an obligate protozoan parasite that naturally infects all mammals, where it alters the host environment to establish chronic infection. Wang and colleagues uncover a new role for the protein...
5.
Nandakumar R, Windross S, Paludan S
Methods Enzymol
. 2019 Aug;
625:1-11.
PMID: 31455521
Type I interferons (IFNα/β) are pivotal to anti-viral defense. Although an absolute requirement for viral clearance, the presence of IFN in high doses sustained over time has been implicated to...
6.
Nandakumar R, Tschismarov R, Meissner F, Prabakaran T, Krissanaprasit A, Farahani E, et al.
Nat Microbiol
. 2019 Feb;
4(4):701-713.
PMID: 30804548
The innate immune system is crucial for eventual control of infections, but may also contribute to pathology. Listeria monocytogenes is an intracellular Gram-positive bacteria and a major cause of food-borne...
7.
Reinert L, Lopusna K, Winther H, Sun C, Thomsen M, Nandakumar R, et al.
Nat Commun
. 2016 Nov;
7:13348.
PMID: 27830700
Herpes simplex encephalitis (HSE) is the most common form of acute viral encephalitis in industrialized countries. Type I interferon (IFN) is important for control of herpes simplex virus (HSV-1) in...
8.
Thomsen M, Nandakumar R, Stadler D, Malo A, Valls R, Wang F, et al.
Hepatology
. 2016 Jun;
64(3):746-59.
PMID: 27312012
Unlabelled: Hepatitis B virus (HBV) is a major human pathogen, and about one third of the global population will be exposed to the virus in their lifetime. HBV infects hepatocytes,...
9.
Iversen M, Reinert L, Thomsen M, Bagdonaite I, Nandakumar R, Cheshenko N, et al.
Nat Immunol
. 2015 Nov;
17(2):150-8.
PMID: 26595890
Mucosal surfaces are exposed to environmental substances and represent a major portal of entry for microorganisms. The innate immune system is responsible for early defense against infections and it is...
10.
Nandakumar R, Paludan S
EMBO Rep
. 2015 Mar;
16(4):397-8.
PMID: 25736437
The innate immune system detects microbes and abnormal self through pattern recognition receptors (PRRs), which detect molecules that are either specific for microbes (such as lipopolysaccharide), present in much higher...